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BIOMARKER:
NRAS G12D
i
Other names:
NRAS1, HRAS1, N-Ras Protein Part 4, Neuroblastoma RAS Viral (V-Ras) Oncogene Homolog, NRAS, Neuroblastoma RAS Viral Oncogene Homolog, NRAS Proto-Oncogene, GTPase
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Entrez ID:
4893
Related biomarkers:
Expression
Mutation
CNA
Others
‹
NRAS overexpression (4)
NRAS expression (1)
NRAS overexpression (4)
NRAS expression (1)
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Associations
News
Trials
VERI cancer hierarchy
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NRAS G12D
Melanoma
NRAS G12D
Melanoma
HL-085
Sensitive: C3 – Early Trials
HL-085
Sensitive
:
C3
HL-085
Sensitive: C3 – Early Trials
HL-085
Sensitive
:
C3
NRAS G12D
Chronic Myelomonocytic Leukemia
NRAS G12D
Chronic Myelomonocytic Leukemia
trametinib
Resistant: C4 – Case Studies
trametinib
Resistant
:
C4
trametinib
Resistant: C4 – Case Studies
trametinib
Resistant
:
C4
NRAS G12D
Non Small Cell Lung Cancer
NRAS G12D
Non Small Cell Lung Cancer
bevacizumab + atezolizumab
Sensitive: C4 – Case Studies
bevacizumab + atezolizumab
Sensitive
:
C4
bevacizumab + atezolizumab
Sensitive: C4 – Case Studies
bevacizumab + atezolizumab
Sensitive
:
C4
NRAS G12D
Prostate Cancer
NRAS G12D
Prostate Cancer
BAY 1125976
Sensitive: D – Preclinical
BAY 1125976
Sensitive
:
D
BAY 1125976
Sensitive: D – Preclinical
BAY 1125976
Sensitive
:
D
NRAS G12D
Acute Lymphocytic Leukemia
NRAS G12D
Acute Lymphocytic Leukemia
U0126
Sensitive: D – Preclinical
U0126
Sensitive
:
D
U0126
Sensitive: D – Preclinical
U0126
Sensitive
:
D
NRAS G12D
Acute Myelogenous Leukemia
NRAS G12D
Acute Myelogenous Leukemia
PD98059
Sensitive: D – Preclinical
PD98059
Sensitive
:
D
PD98059
Sensitive: D – Preclinical
PD98059
Sensitive
:
D
NRAS G12D
Chronic Myelomonocytic Leukemia
NRAS G12D
Chronic Myelomonocytic Leukemia
selumetinib
Resistant: D – Preclinical
selumetinib
Resistant
:
D
selumetinib
Resistant: D – Preclinical
selumetinib
Resistant
:
D
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