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BIOMARKER:

NPM1 mutation

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Other names: Nucleophosmin (Nucleolar Phosphoprotein B23, Numatrin), Testicular Tissue Protein Li 128, Nucleolar Protein NO38, Numatrin, NPM1, Nucleophosmin 1, Nucleophosmin/Nucleoplasmin Family, Member 1, Nucleolar Phosphoprotein B23
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Entrez ID:
Related biomarkers:
NPM1 mutation
Acute Myelogenous Leukemia
gemtuzumab ozogamicin
Sensitive
:
A2
NPM1 mutation
Acute Myelogenous Leukemia
venetoclax
Sensitive
:
B
NPM1 mutation
Acute Myelogenous Leukemia
cytarabine
Sensitive
:
B
NPM1 mutation
Acute Myelogenous Leukemia
azacitidine
Sensitive
:
B
NPM1 mutation
Acute Myelogenous Leukemia
SNDX-5613
Sensitive
:
B
NPM1 mutation
Acute Myelogenous Leukemia
cytarabine + idarubicin hydrochloride
Sensitive
:
C2
NPM1 mutation
Acute Myelogenous Leukemia
dactinomycin
Sensitive
:
C2
NPM1 mutation
Acute Myelogenous Leukemia
GS-9973
Sensitive
:
C2
NPM1 mutation
Acute Myelogenous Leukemia
sorafenib
Sensitive
:
C2
NPM1 mutation
Leukemia
SNDX-5613
Sensitive
:
C2
NPM1 mutation
Acute Myelogenous Leukemia
cytarabine / daunorubicin liposomal formulation
Sensitive
:
C3
NPM1 mutation
Acute Myelogenous Leukemia
cytarabine
Sensitive
:
C3
NPM1 mutation
Acute Myelogenous Leukemia
FLAI
Sensitive
:
C3
NPM1 mutation
Chronic Myelomonocytic Leukemia
venetoclax
Sensitive
:
C3
NPM1 mutation
Myelodysplastic Syndrome
decitabine
Sensitive
:
C3
NPM1 mutation
Acute Myelogenous Leukemia
quizartinib
Sensitive
:
C3
NPM1 mutation
Acute Myelogenous Leukemia
venetoclax + ruxolitinib
Sensitive
:
C3
NPM1 mutation
Myelodysplastic Syndrome
azacitidine
Resistant
:
C3
NPM1 mutation
Acute Myelogenous Leukemia
cytarabine + clofarabine
Sensitive
:
C3
NPM1 mutation
Acute Myelogenous Leukemia
cytarabine + cladribine
Sensitive
:
C3
NPM1 mutation
Acute Myelogenous Leukemia
decitabine + clofarabine
Sensitive
:
C3
NPM1 mutation
Acute Myelogenous Leukemia
decitabine + cladribine
Sensitive
:
C3
NPM1 mutation
Acute Myelogenous Leukemia
PD1 inhibitor
Sensitive
:
C3
NPM1 mutation
Acute Myelogenous Leukemia
venetoclax + gilteritinib
Sensitive
:
C3
NPM1 mutation
Acute Myelogenous Leukemia
ARO-002
Sensitive
:
C3
NPM1 mutation
Acute Myelogenous Leukemia
ABBV-744
Sensitive
:
D
NPM1 mutation
Acute Myelogenous Leukemia
venetoclax + IACS-010759
Sensitive
:
D
NPM1 mutation
Leukemia
EPZ004777
Sensitive
:
D
NPM1 mutation
Acute Myelogenous Leukemia
NSC348884
Sensitive
:
D
NPM1 mutation
Acute Myelogenous Leukemia
DS-M1
Sensitive
:
D
NPM1 mutation
Acute Myelogenous Leukemia
abemaciclib + KO-539
Sensitive
:
D
NPM1 mutation
Acute Myelogenous Leukemia
KO-539 + OTX015
Sensitive
:
D