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BIOMARKER:
NOTCH1 positive + FGFR2 mutation
i
Other names:
NOTCH1, TAN1, FGFR2, BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, Fibroblast growth factor receptor 2
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Entrez ID:
2263
;
4851
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
FGFR2 mutation (30)
NOTCH1 mutation (23)
FGFR2 N549K (7)
FGFR2 rearrangement (7)
FGFR2 P253R (3)
FGFR2 K310R (2)
FGFR2 translocation (2)
NOTCH1 C478F (2)
ARID1A K1238fs + FGFR2 R210Q (1)
BAP1 mutation + FGFR2 rearrangement (1)
FDFT1 rearrangement + FGFR2 rearrangement (1)
FGFR2 A391E (1)
FGFR2 B252W (1)
FGFR2 C382R (1)
FGFR2 E250G (1)
FGFR2 E565A (1)
FGFR2 E565G (1)
FGFR2 E565K (1)
FGFR2 F276C (1)
FGFR2 M540_I541insMM (1)
FGFR2 N549D (1)
FGFR2 N549H (1)
FGFR2 N549T (1)
FGFR2 N550K (1)
FGFR2 S252W (1)
FGFR2 V564F (1)
FGFR2 V564I (1)
FGFR2 V564L (1)
FGFR2 Y375C (1)
FGFR2 Y376C (1)
PIK3CA mutation + FGFR2 rearrangement (1)
PIK3CB mutation + FGFR2 rearrangement (1)
PIK3R1 mutation + FGFR2 rearrangement (1)
TP53 mutation + FGFR2 rearrangement (1)
EGFR mutation + NOTCH1 mutation (1)
NOTCH1 A1524V (1)
NOTCH1 C344fs (1)
NOTCH1 E1679 (1)
NOTCH1 E694 (1)
NOTCH1 F1592C (1)
NOTCH1 F1592S (1)
NOTCH1 F357del (1)
NOTCH1 G192 (1)
NOTCH1 G72R (1)
NOTCH1 H2018fs (1)
NOTCH1 L1574P (1)
NOTCH1 L1574Q (1)
NOTCH1 L1585R (1)
NOTCH1 L1600P (1)
NOTCH1 L1600Q (1)
NOTCH1 Q1957 (1)
NOTCH1 V1577A (1)
NOTCH1 V1577E (1)
NOTCH1 V489fs (1)
FGFR2 C383R (0)
FGFR2 K660N (0)
FGFR2 W290C (0)
FGFR2 wild-type (0)
FGFR2 mutation (30)
NOTCH1 mutation (23)
FGFR2 N549K (7)
FGFR2 rearrangement (7)
FGFR2 P253R (3)
FGFR2 K310R (2)
FGFR2 translocation (2)
NOTCH1 C478F (2)
ARID1A K1238fs + FGFR2 R210Q (1)
BAP1 mutation + FGFR2 rearrangement (1)
FDFT1 rearrangement + FGFR2 rearrangement (1)
FGFR2 A391E (1)
FGFR2 B252W (1)
FGFR2 C382R (1)
FGFR2 E250G (1)
FGFR2 E565A (1)
FGFR2 E565G (1)
FGFR2 E565K (1)
FGFR2 F276C (1)
FGFR2 M540_I541insMM (1)
FGFR2 N549D (1)
FGFR2 N549H (1)
FGFR2 N549T (1)
FGFR2 N550K (1)
FGFR2 S252W (1)
FGFR2 V564F (1)
FGFR2 V564I (1)
FGFR2 V564L (1)
FGFR2 Y375C (1)
FGFR2 Y376C (1)
PIK3CA mutation + FGFR2 rearrangement (1)
PIK3CB mutation + FGFR2 rearrangement (1)
PIK3R1 mutation + FGFR2 rearrangement (1)
TP53 mutation + FGFR2 rearrangement (1)
EGFR mutation + NOTCH1 mutation (1)
NOTCH1 A1524V (1)
NOTCH1 C344fs (1)
NOTCH1 E1679 (1)
NOTCH1 E694 (1)
NOTCH1 F1592C (1)
NOTCH1 F1592S (1)
NOTCH1 F357del (1)
NOTCH1 G192 (1)
NOTCH1 G72R (1)
NOTCH1 H2018fs (1)
NOTCH1 L1574P (1)
NOTCH1 L1574Q (1)
NOTCH1 L1585R (1)
NOTCH1 L1600P (1)
NOTCH1 L1600Q (1)
NOTCH1 Q1957 (1)
NOTCH1 V1577A (1)
NOTCH1 V1577E (1)
NOTCH1 V489fs (1)
FGFR2 C383R (0)
FGFR2 K660N (0)
FGFR2 W290C (0)
FGFR2 wild-type (0)
›
Associations
News
Trials
VERI cancer hierarchy
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NOTCH1 positive + FGFR2 mutation
Adenoid Cystic Carcinoma
NOTCH1 positive + FGFR2 mutation
Adenoid Cystic Carcinoma
lenvatinib + erdafitinib + γ-secretase inhibitor
Sensitive: C4 – Case Studies
lenvatinib + erdafitinib + γ-secretase inhibitor
Sensitive
:
C4
lenvatinib + erdafitinib + γ-secretase inhibitor
Sensitive: C4 – Case Studies
lenvatinib + erdafitinib + γ-secretase inhibitor
Sensitive
:
C4
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