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CANCER:
Neuroblastoma
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Associations
(59)
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No biomarker
Neuroblastoma
No biomarker
Neuroblastoma
dinutuximab beta
Sensitive: A1 - Approval
dinutuximab beta
Sensitive
:
A1
dinutuximab beta
Sensitive: A1 - Approval
dinutuximab beta
Sensitive
:
A1
No biomarker
Neuroblastoma
No biomarker
Neuroblastoma
doxorubicin hydrochloride
Sensitive: A1 - Approval
doxorubicin hydrochloride
Sensitive
:
A1
doxorubicin hydrochloride
Sensitive: A1 - Approval
doxorubicin hydrochloride
Sensitive
:
A1
No biomarker
Neuroblastoma
No biomarker
Neuroblastoma
melphalan
Sensitive: A1 - Approval
melphalan
Sensitive
:
A1
melphalan
Sensitive: A1 - Approval
melphalan
Sensitive
:
A1
No biomarker
Neuroblastoma
No biomarker
Neuroblastoma
dinutuximab
Sensitive: A1 - Approval
dinutuximab
Sensitive
:
A1
dinutuximab
Sensitive: A1 - Approval
dinutuximab
Sensitive
:
A1
No biomarker
Neuroblastoma
No biomarker
Neuroblastoma
cyclophosphamide
Sensitive: A1 - Approval
cyclophosphamide
Sensitive
:
A1
cyclophosphamide
Sensitive: A1 - Approval
cyclophosphamide
Sensitive
:
A1
No biomarker
Neuroblastoma
No biomarker
Neuroblastoma
naxitamab-gqgk
Sensitive: A1 - Approval
naxitamab-gqgk
Sensitive
:
A1
naxitamab-gqgk
Sensitive: A1 - Approval
naxitamab-gqgk
Sensitive
:
A1
No biomarker
Neuroblastoma
No biomarker
Neuroblastoma
eflornithine
Sensitive: A1 - Approval
eflornithine
Sensitive
:
A1
eflornithine
Sensitive: A1 - Approval
eflornithine
Sensitive
:
A1
ALK positive
Neuroblastoma
ALK positive
Neuroblastoma
lorlatinib
Sensitive: C1 - Off-label
lorlatinib
Sensitive
:
C1
lorlatinib
Sensitive: C1 - Off-label
lorlatinib
Sensitive
:
C1
ALK mutation
Neuroblastoma
ALK mutation
Neuroblastoma
lorlatinib
Sensitive: C2 – Inclusion Criteria
lorlatinib
Sensitive
:
C2
lorlatinib
Sensitive: C2 – Inclusion Criteria
lorlatinib
Sensitive
:
C2
ALK positive
Neuroblastoma
ALK positive
Neuroblastoma
crizotinib
Sensitive: C3 – Early Trials
crizotinib
Sensitive
:
C3
crizotinib
Sensitive: C3 – Early Trials
crizotinib
Sensitive
:
C3
ALK R1275Q
Neuroblastoma
ALK R1275Q
Neuroblastoma
crizotinib
Sensitive: C3 – Early Trials
crizotinib
Sensitive
:
C3
crizotinib
Sensitive: C3 – Early Trials
crizotinib
Sensitive
:
C3
ATRX mutation
Neuroblastoma
ATRX mutation
Neuroblastoma
AZD1775
Sensitive: C3 – Early Trials
AZD1775
Sensitive
:
C3
AZD1775
Sensitive: C3 – Early Trials
AZD1775
Sensitive
:
C3
MYCN positive
Neuroblastoma
MYCN positive
Neuroblastoma
dasatinib + temozolomide + sirolimus
Sensitive: C3 – Early Trials
dasatinib + temozolomide + sirolimus
Sensitive
:
C3
dasatinib + temozolomide + sirolimus
Sensitive: C3 – Early Trials
dasatinib + temozolomide + sirolimus
Sensitive
:
C3
ALK rearrangement + ALK R1275Q + TP53 mutation
Neuroblastoma
ALK rearrangement + ALK R1275Q + TP53 mutation
Neuroblastoma
crizotinib
Resistant: C4 – Case Studies
crizotinib
Resistant
:
C4
crizotinib
Resistant: C4 – Case Studies
crizotinib
Resistant
:
C4
ALK R1275Q
Neuroblastoma
ALK R1275Q
Neuroblastoma
lorlatinib
Sensitive: C4 – Case Studies
lorlatinib
Sensitive
:
C4
lorlatinib
Sensitive: C4 – Case Studies
lorlatinib
Sensitive
:
C4
PGBD5 overexpression
Neuroblastoma
PGBD5 overexpression
Neuroblastoma
cisplatin
Sensitive: D – Preclinical
cisplatin
Sensitive
:
D
cisplatin
Sensitive: D – Preclinical
cisplatin
Sensitive
:
D
PGBD5 overexpression
Neuroblastoma
PGBD5 overexpression
Neuroblastoma
AZD6738
Sensitive: D – Preclinical
AZD6738
Sensitive
:
D
AZD6738
Sensitive: D – Preclinical
AZD6738
Sensitive
:
D
PGBD5 underexpression
Neuroblastoma
PGBD5 underexpression
Neuroblastoma
AZD6738
Sensitive: D – Preclinical
AZD6738
Sensitive
:
D
AZD6738
Sensitive: D – Preclinical
AZD6738
Sensitive
:
D
ALK R1275Q
Neuroblastoma
ALK R1275Q
Neuroblastoma
TAE-684
Resistant: D – Preclinical
TAE-684
Resistant
:
D
TAE-684
Resistant: D – Preclinical
TAE-684
Resistant
:
D
MYCN amplification
Neuroblastoma
MYCN amplification
Neuroblastoma
panobinostat + GSK2816126
Sensitive: D – Preclinical
panobinostat + GSK2816126
Sensitive
:
D
panobinostat + GSK2816126
Sensitive: D – Preclinical
panobinostat + GSK2816126
Sensitive
:
D
MYCN amplification
Neuroblastoma
MYCN amplification
Neuroblastoma
OTX015
Sensitive: D – Preclinical
OTX015
Sensitive
:
D
OTX015
Sensitive: D – Preclinical
OTX015
Sensitive
:
D
MYCN amplification
Neuroblastoma
MYCN amplification
Neuroblastoma
JQ-1 + panobinostat
Sensitive: D – Preclinical
JQ-1 + panobinostat
Sensitive
:
D
JQ-1 + panobinostat
Sensitive: D – Preclinical
JQ-1 + panobinostat
Sensitive
:
D
MYCN amplification
Neuroblastoma
MYCN amplification
Neuroblastoma
brigatinib
Resistant: D – Preclinical
brigatinib
Resistant
:
D
brigatinib
Resistant: D – Preclinical
brigatinib
Resistant
:
D
MYCN amplification
Neuroblastoma
MYCN amplification
Neuroblastoma
crizotinib
Resistant: D – Preclinical
crizotinib
Resistant
:
D
crizotinib
Resistant: D – Preclinical
crizotinib
Resistant
:
D
ALK F1174L
Neuroblastoma
ALK F1174L
Neuroblastoma
crizotinib
Resistant: D – Preclinical
crizotinib
Resistant
:
D
crizotinib
Resistant: D – Preclinical
crizotinib
Resistant
:
D
ALK F1174L
Neuroblastoma
ALK F1174L
Neuroblastoma
AZD3463
Sensitive: D – Preclinical
AZD3463
Sensitive
:
D
AZD3463
Sensitive: D – Preclinical
AZD3463
Sensitive
:
D
ALK F1174L
Neuroblastoma
ALK F1174L
Neuroblastoma
alectinib
Sensitive: D – Preclinical
alectinib
Sensitive
:
D
alectinib
Sensitive: D – Preclinical
alectinib
Sensitive
:
D
ALK amplification
Neuroblastoma
ALK amplification
Neuroblastoma
alectinib
Sensitive: D – Preclinical
alectinib
Sensitive
:
D
alectinib
Sensitive: D – Preclinical
alectinib
Sensitive
:
D
ALK F1245C
Neuroblastoma
ALK F1245C
Neuroblastoma
lorlatinib
Sensitive: D – Preclinical
lorlatinib
Sensitive
:
D
lorlatinib
Sensitive: D – Preclinical
lorlatinib
Sensitive
:
D
ALK F1174C
Neuroblastoma
ALK F1174C
Neuroblastoma
lorlatinib
Sensitive: D – Preclinical
lorlatinib
Sensitive
:
D
lorlatinib
Sensitive: D – Preclinical
lorlatinib
Sensitive
:
D
ALK F1174L
Neuroblastoma
ALK F1174L
Neuroblastoma
TAE-684
Sensitive: D – Preclinical
TAE-684
Sensitive
:
D
TAE-684
Sensitive: D – Preclinical
TAE-684
Sensitive
:
D
MYCN amplification + ALK rearrangement
Neuroblastoma
MYCN amplification + ALK rearrangement
Neuroblastoma
brigatinib
Sensitive: D – Preclinical
brigatinib
Sensitive
:
D
brigatinib
Sensitive: D – Preclinical
brigatinib
Sensitive
:
D
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