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BIOMARKER:
MYD88 mutation
i
Other names:
MYD88, MYD88 Innate Immune Signal Transduction Adaptor, Myeloid Differentiation Primary Response Protein MyD88, Myeloid Differentiation Primary Response Gene (88), Myeloid Differentiation Primary Response 88, Mutant Myeloid Differentiation Primary Response 88, MYD88D
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Entrez ID:
4615
Related biomarkers:
Expression
Mutation
Others
‹
MYD88 L265P (13)
MYD88 L265P + BRAF V600E (2)
MYD88 L265P + CD79B mutation (2)
MYD88 mutation + CXCR4 mutation (2)
MYD88 L265P + CXCR4 mutation (1)
MYD88 mutation + CD79B mutation (1)
MYD88 wild-type (1)
BTK C481S + MYD88 mutation (0)
MYD88 L265P (13)
MYD88 L265P + BRAF V600E (2)
MYD88 L265P + CD79B mutation (2)
MYD88 mutation + CXCR4 mutation (2)
MYD88 L265P + CXCR4 mutation (1)
MYD88 mutation + CD79B mutation (1)
MYD88 wild-type (1)
BTK C481S + MYD88 mutation (0)
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MYD88 mutation
Waldenstrom Macroglobulinemia
MYD88 mutation
Waldenstrom Macroglobulinemia
zanubrutinib
Sensitive: B - Late Trials
zanubrutinib
Sensitive
:
B
zanubrutinib
Sensitive: B - Late Trials
zanubrutinib
Sensitive
:
B
MYD88 mutation
Waldenstrom Macroglobulinemia
MYD88 mutation
Waldenstrom Macroglobulinemia
ibrutinib
Sensitive: C2 – Inclusion Criteria
ibrutinib
Sensitive
:
C2
ibrutinib
Sensitive: C2 – Inclusion Criteria
ibrutinib
Sensitive
:
C2
MYD88 mutation
Lymphoma
MYD88 mutation
Lymphoma
ibrutinib
Sensitive: C2 – Inclusion Criteria
ibrutinib
Sensitive
:
C2
ibrutinib
Sensitive: C2 – Inclusion Criteria
ibrutinib
Sensitive
:
C2
MYD88 mutation
Diffuse Large B Cell Lymphoma
MYD88 mutation
Diffuse Large B Cell Lymphoma
orelabrutinib
Sensitive: C2 – Inclusion Criteria
orelabrutinib
Sensitive
:
C2
orelabrutinib
Sensitive: C2 – Inclusion Criteria
orelabrutinib
Sensitive
:
C2
MYD88 mutation
Marginal Zone Lymphoma
MYD88 mutation
Marginal Zone Lymphoma
ibrutinib
Sensitive: C3 – Early Trials
ibrutinib
Sensitive
:
C3
ibrutinib
Sensitive: C3 – Early Trials
ibrutinib
Sensitive
:
C3
MYD88 mutation
Diffuse Large B Cell Lymphoma
MYD88 mutation
Diffuse Large B Cell Lymphoma
ibrutinib
Sensitive: C3 – Early Trials
ibrutinib
Sensitive
:
C3
ibrutinib
Sensitive: C3 – Early Trials
ibrutinib
Sensitive
:
C3
MYD88 mutation
Diffuse Large B Cell Lymphoma
MYD88 mutation
Diffuse Large B Cell Lymphoma
methotrexate
Sensitive: C3 – Early Trials
methotrexate
Sensitive
:
C3
methotrexate
Sensitive: C3 – Early Trials
methotrexate
Sensitive
:
C3
MYD88 mutation
Marginal Zone Lymphoma
MYD88 mutation
Marginal Zone Lymphoma
zanubrutinib
Sensitive: C3 – Early Trials
zanubrutinib
Sensitive
:
C3
zanubrutinib
Sensitive: C3 – Early Trials
zanubrutinib
Sensitive
:
C3
MYD88 mutation
Lymphoma
MYD88 mutation
Lymphoma
rituximab + orelabrutinib
Sensitive: C3 – Early Trials
rituximab + orelabrutinib
Sensitive
:
C3
rituximab + orelabrutinib
Sensitive: C3 – Early Trials
rituximab + orelabrutinib
Sensitive
:
C3
MYD88 mutation
Lymphoma
MYD88 mutation
Lymphoma
rituximab + lenalidomide + acalabrutinib
Sensitive: C3 – Early Trials
rituximab + lenalidomide + acalabrutinib
Sensitive
:
C3
rituximab + lenalidomide + acalabrutinib
Sensitive: C3 – Early Trials
rituximab + lenalidomide + acalabrutinib
Sensitive
:
C3
MYD88 mutation
Waldenstrom Macroglobulinemia
MYD88 mutation
Waldenstrom Macroglobulinemia
BTK inhibitor
Sensitive: C3 – Early Trials
BTK inhibitor
Sensitive
:
C3
BTK inhibitor
Sensitive: C3 – Early Trials
BTK inhibitor
Sensitive
:
C3
MYD88 mutation
Diffuse Large B Cell Lymphoma
MYD88 mutation
Diffuse Large B Cell Lymphoma
pomalidomide
Sensitive: C3 – Early Trials
pomalidomide
Sensitive
:
C3
pomalidomide
Sensitive: C3 – Early Trials
pomalidomide
Sensitive
:
C3
MYD88 mutation
Diffuse Large B Cell Lymphoma
MYD88 mutation
Diffuse Large B Cell Lymphoma
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
MYD88 mutation
Waldenstrom Macroglobulinemia
MYD88 mutation
Waldenstrom Macroglobulinemia
rituximab
Sensitive: C4 – Case Studies
rituximab
Sensitive
:
C4
rituximab
Sensitive: C4 – Case Studies
rituximab
Sensitive
:
C4
MYD88 mutation
Diffuse Large B Cell Lymphoma
MYD88 mutation
Diffuse Large B Cell Lymphoma
BTK inhibitor + KT-413
Sensitive: D – Preclinical
BTK inhibitor + KT-413
Sensitive
:
D
BTK inhibitor + KT-413
Sensitive: D – Preclinical
BTK inhibitor + KT-413
Sensitive
:
D
MYD88 mutation
Diffuse Large B Cell Lymphoma
MYD88 mutation
Diffuse Large B Cell Lymphoma
rituximab + KT-413
Sensitive: D – Preclinical
rituximab + KT-413
Sensitive
:
D
rituximab + KT-413
Sensitive: D – Preclinical
rituximab + KT-413
Sensitive
:
D
MYD88 mutation
Diffuse Large B Cell Lymphoma
MYD88 mutation
Diffuse Large B Cell Lymphoma
KT-413
Sensitive: D – Preclinical
KT-413
Sensitive
:
D
KT-413
Sensitive: D – Preclinical
KT-413
Sensitive
:
D
MYD88 mutation
Diffuse Large B Cell Lymphoma
MYD88 mutation
Diffuse Large B Cell Lymphoma
BTM-3566
Sensitive: D – Preclinical
BTM-3566
Sensitive
:
D
BTM-3566
Sensitive: D – Preclinical
BTM-3566
Sensitive
:
D
MYD88 mutation
Diffuse Large B Cell Lymphoma
MYD88 mutation
Diffuse Large B Cell Lymphoma
pacritinib
Sensitive: D – Preclinical
pacritinib
Sensitive
:
D
pacritinib
Sensitive: D – Preclinical
pacritinib
Sensitive
:
D
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