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BIOMARKER:

MYC overexpression + IDH2 mutation

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Other names: MYC, bHLHe39, c-Myc, MYCC, V-myc avian myelocytomatosis viral oncogene homolog, IDH2, Isocitrate Dehydrogenase (NADP(+)) 2, Isocitrate Dehydrogenase (NADP(+)) 2, Mitochondrial, Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial, Isocitrate Dehydrogenase [NADP], Mitochondrial, Oxalosuccinate Decarboxylase, NADP(+)-Specific ICDH, ICD-M, IDH, IDP, MNADP-IDH, D2HGA2, IDHM, IDPM
Entrez ID:
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Trials
MYC overexpression + IDH2 mutation
AML
enasidenib
Resistant: C3 – Early Trials
SOHO 2021 - 3 weeks
MYC overexpression + IDH2 mutation
AML
ivosidenib
Resistant: C3 – Early Trials
SOHO 2021 - 3 weeks