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Association details:
| Biomarker: | MYB-NFIB fusion |
|---|---|
| Cancer: | Adenoid Cystic Carcinoma |
| Drug: | berzosertib (M6620) (ATR inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
ATR is a MYB regulated gene and potential therapeutic target in adenoid cystic carcinoma
Published date:
01/30/2020
Excerpt:
Treatment of cultured MYB-NFIB positive ACC cells (ACC 1 and ACC 2) with VX-970 generated a dose-dependent decrease in proliferation and a significant increase in apoptosis…
DOI:
10.1038/s41389-020-0194-3
