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DRUG CLASS:

ATR inhibitor

DRUG CLASS:

ATR inhibitor

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Related drugs:

DDR	Cervical Cancer	DDR	Cervical Cancer	BAY 1895344 Sensitive: C2 – Inclusion Criteria BAY 1895344 Sensitive : C2	BAY 1895344 Sensitive: C2 – Inclusion Criteria BAY 1895344 Sensitive : C2
ATM deletion	Colorectal Cancer	ATM deletion	Colorectal Cancer	M6620 Sensitive: C3 – Early Trials M6620 Sensitive : C3	M6620 Sensitive: C3 – Early Trials M6620 Sensitive : C3
BRCA1 mutation	HER2 Negative Breast Cancer	BRCA1 mutation	HER2 Negative Breast Cancer	olaparib + AZD6738 Sensitive: C3 – Early Trials olaparib + AZD6738 Sensitive : C3	olaparib + AZD6738 Sensitive: C3 – Early Trials olaparib + AZD6738 Sensitive : C3
BRCA2 mutation	HER2 Negative Breast Cancer	BRCA2 mutation	HER2 Negative Breast Cancer	olaparib + AZD6738 Sensitive: C3 – Early Trials olaparib + AZD6738 Sensitive : C3	olaparib + AZD6738 Sensitive: C3 – Early Trials olaparib + AZD6738 Sensitive : C3
BRCA1 mutation	Ovarian Cancer	BRCA1 mutation	Ovarian Cancer	BAY 1895344 Sensitive: C3 – Early Trials BAY 1895344 Sensitive : C3	BAY 1895344 Sensitive: C3 – Early Trials BAY 1895344 Sensitive : C3
ATM expression + ATM T2333fs* + EGFR negative	HER2 Negative Breast Cancer	ATM expression + ATM T2333fs* + EGFR negative	HER2 Negative Breast Cancer	BAY 1895344 Sensitive: C3 – Early Trials BAY 1895344 Sensitive : C3	BAY 1895344 Sensitive: C3 – Early Trials BAY 1895344 Sensitive : C3
ATM PI2629fs*	Endometrial Cancer	ATM PI2629fs*	Endometrial Cancer	BAY 1895344 Sensitive: C3 – Early Trials BAY 1895344 Sensitive : C3	BAY 1895344 Sensitive: C3 – Early Trials BAY 1895344 Sensitive : C3
ATM mutation	Solid Tumor	ATM mutation	Solid Tumor	BAY 1895344 Sensitive: C3 – Early Trials BAY 1895344 Sensitive : C3	BAY 1895344 Sensitive: C3 – Early Trials BAY 1895344 Sensitive : C3
JAK2 underexpression	Cutaneous Melanoma	JAK2 underexpression	Cutaneous Melanoma	QL-VIII-58 Sensitive: C3 – Early Trials QL-VIII-58 Sensitive : C3	QL-VIII-58 Sensitive: C3 – Early Trials QL-VIII-58 Sensitive : C3
BRCA1 mutation	Ovarian Cancer	BRCA1 mutation	Ovarian Cancer	M6620 Sensitive: C3 – Early Trials M6620 Sensitive : C3	M6620 Sensitive: C3 – Early Trials M6620 Sensitive : C3
NRAS mutation	Melanoma	NRAS mutation	Melanoma	AZD6738 Sensitive: C3 – Early Trials AZD6738 Sensitive : C3	AZD6738 Sensitive: C3 – Early Trials AZD6738 Sensitive : C3
NF1 mutation	Colorectal Cancer	NF1 mutation	Colorectal Cancer	AZD6738 Sensitive: C3 – Early Trials AZD6738 Sensitive : C3	AZD6738 Sensitive: C3 – Early Trials AZD6738 Sensitive : C3