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BIOMARKER:
MLL rearrangement
i
Other names:
HTRX1, HTRX, MLL1A, Mixed Lineage Leukemia 1, Myeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 1, CXXC7, MLL1, TRX1, Zinc Finger Protein HRX, Trithorax-Like Protein, ALL-1, Lysine (K)-Specific Methyltransferase 2A, CXXC-Type Zinc Finger Protein 7, Histone-Lysine N-Methyltransferase 2A, Myeloid/Lymphoid Or Mixed-Lineage Leukemia, Lysine Methyltransferase 2A, MLL, Myeloid/Lymphoid Or Mixed-Lineage Leukemia, KMT2A
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Associations
News
Trials
VERI cancer hierarchy
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MLL rearrangement
Acute Myelogenous Leukemia
MLL rearrangement
Acute Myelogenous Leukemia
revumenib
Sensitive: B - Late Trials
revumenib
Sensitive
:
B
revumenib
Sensitive: B - Late Trials
revumenib
Sensitive
:
B
MLL rearrangement
Leukemia
MLL rearrangement
Leukemia
revumenib
Sensitive: C2 – Inclusion Criteria
revumenib
Sensitive
:
C2
revumenib
Sensitive: C2 – Inclusion Criteria
revumenib
Sensitive
:
C2
MLL rearrangement
Acute Lymphocytic Leukemia
MLL rearrangement
Acute Lymphocytic Leukemia
CB-659
Sensitive: D – Preclinical
CB-659
Sensitive
:
D
CB-659
Sensitive: D – Preclinical
CB-659
Sensitive
:
D
MLL rearrangement
Acute Lymphocytic Leukemia
MLL rearrangement
Acute Lymphocytic Leukemia
irinotecan
Sensitive: D – Preclinical
irinotecan
Sensitive
:
D
irinotecan
Sensitive: D – Preclinical
irinotecan
Sensitive
:
D
MLL rearrangement
Acute Lymphocytic Leukemia
MLL rearrangement
Acute Lymphocytic Leukemia
doxorubicin hydrochloride + APH-0202
Sensitive: D – Preclinical
doxorubicin hydrochloride + APH-0202
Sensitive
:
D
doxorubicin hydrochloride + APH-0202
Sensitive: D – Preclinical
doxorubicin hydrochloride + APH-0202
Sensitive
:
D
MLL rearrangement
B Acute Lymphoblastic Leukemia
MLL rearrangement
B Acute Lymphoblastic Leukemia
OSE-127
Sensitive: D – Preclinical
OSE-127
Sensitive
:
D
OSE-127
Sensitive: D – Preclinical
OSE-127
Sensitive
:
D
MLL rearrangement
Leukemia
MLL rearrangement
Leukemia
D0060-319
Sensitive: D – Preclinical
D0060-319
Sensitive
:
D
D0060-319
Sensitive: D – Preclinical
D0060-319
Sensitive
:
D
MLL rearrangement
Acute Myelogenous Leukemia
MLL rearrangement
Acute Myelogenous Leukemia
selinexor + KO-539
Sensitive: D – Preclinical
selinexor + KO-539
Sensitive
:
D
selinexor + KO-539
Sensitive: D – Preclinical
selinexor + KO-539
Sensitive
:
D
MLL rearrangement
Acute Myelogenous Leukemia
MLL rearrangement
Acute Myelogenous Leukemia
revumenib + ORY-1001
Sensitive: D – Preclinical
revumenib + ORY-1001
Sensitive
:
D
revumenib + ORY-1001
Sensitive: D – Preclinical
revumenib + ORY-1001
Sensitive
:
D
MLL rearrangement
Leukemia
MLL rearrangement
Leukemia
VTP-50469 + EPZ-5676
Sensitive: D – Preclinical
VTP-50469 + EPZ-5676
Sensitive
:
D
VTP-50469 + EPZ-5676
Sensitive: D – Preclinical
VTP-50469 + EPZ-5676
Sensitive
:
D
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