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    BIOMARKER:

    MLL rearrangement

    i
    Other names: HTRX1, HTRX, MLL1A, Mixed Lineage Leukemia 1, Myeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 1, CXXC7, MLL1, TRX1, Zinc Finger Protein HRX, Trithorax-Like Protein, ALL-1, Lysine (K)-Specific Methyltransferase 2A, CXXC-Type Zinc Finger Protein 7, Histone-Lysine N-Methyltransferase 2A, Myeloid/Lymphoid Or Mixed-Lineage Leukemia, Lysine Methyltransferase 2A, MLL, Myeloid/Lymphoid Or Mixed-Lineage Leukemia, KMT2A
    MLL rearrangement
    Acute Myelogenous Leukemia
    palbociclib
    Sensitive
    :
    C2
    MLL rearrangement
    Acute Myelogenous Leukemia
    venetoclax
    Sensitive
    :
    C2
    MLL rearrangement
    Acute Myelogenous Leukemia
    abemaciclib
    Sensitive
    :
    C3
    MLL rearrangement
    Acute Lymphocytic Leukemia
    blinatumomab + inotuzumab ozogamicin
    Resistant
    :
    C3
    MLL rearrangement
    Acute Lymphocytic Leukemia
    inotuzumab ozogamicin
    Resistant
    :
    C3
    MLL rearrangement
    Acute Myelogenous Leukemia
    KO-539
    Sensitive
    :
    C3
    MLL rearrangement
    B Acute Lymphoblastic Leukemia
    blinatumomab
    Resistant
    :
    C3
    MLL rearrangement
    Childhood B Acute Lymphoblastic Leukemia
    MK-2206
    Sensitive
    :
    D
    MLL rearrangement
    B Acute Lymphoblastic Leukemia
    venetoclax
    Sensitive
    :
    D
    MLL rearrangement
    Leukemia
    JQ-1
    Sensitive
    :
    D