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BIOMARKER:
MET positive
i
Other names:
DFNB97, AUTS9, RCCP2, C-Met, HGFR, HGF Receptor, Met Proto-Oncogene, HGF/SF Receptor, Proto-Oncogene C-Met, Scatter Factor Receptor, Tyrosine-Protein Kinase Met, Hepatocyte Growth Factor Receptor, MET, MET Proto-Oncogene, Receptor Tyrosine Kinase
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Entrez ID:
4233
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
MET overexpression (32)
MET expression (12)
EGFR expression + MET expression (2)
MET overexpression + KDR overexpression (2)
MET overexpression + SYK overexpression (2)
TPBG expression + MET expression (2)
FGFR overexpression + MET overexpression (1)
MET expression + HER-2 expression (1)
MET overexpression + HER-2 overexpression (1)
MET overexpression + MUC5B overexpression (1)
MET underexpression (1)
PTGS2 positive + MET positive + TOPK positive + EGFR mutation (0)
MET overexpression (32)
MET expression (12)
EGFR expression + MET expression (2)
MET overexpression + KDR overexpression (2)
MET overexpression + SYK overexpression (2)
TPBG expression + MET expression (2)
FGFR overexpression + MET overexpression (1)
MET expression + HER-2 expression (1)
MET overexpression + HER-2 overexpression (1)
MET overexpression + MUC5B overexpression (1)
MET underexpression (1)
PTGS2 positive + MET positive + TOPK positive + EGFR mutation (0)
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Associations
News
Trials
VERI cancer hierarchy
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MET positive
Solid Tumor
MET positive
Solid Tumor
GST-HG16
Sensitive: C2 – Inclusion Criteria
GST-HG16
Sensitive
:
C2
GST-HG16
Sensitive: C2 – Inclusion Criteria
GST-HG16
Sensitive
:
C2
MET positive
Non Small Cell Lung Cancer
MET positive
Non Small Cell Lung Cancer
ABBV-399
Sensitive: C2 – Inclusion Criteria
ABBV-399
Sensitive
:
C2
ABBV-399
Sensitive: C2 – Inclusion Criteria
ABBV-399
Sensitive
:
C2
MET positive
Squamous Cell Carcinoma of Head and Neck
MET positive
Squamous Cell Carcinoma of Head and Neck
nivolumab
Resistant: C3 – Early Trials
nivolumab
Resistant
:
C3
nivolumab
Resistant: C3 – Early Trials
nivolumab
Resistant
:
C3
MET positive
Lung Non-Squamous Non-Small Cell Cancer
MET positive
Lung Non-Squamous Non-Small Cell Cancer
erlotinib + ABBV-399
Sensitive: C3 – Early Trials
erlotinib + ABBV-399
Sensitive
:
C3
erlotinib + ABBV-399
Sensitive: C3 – Early Trials
erlotinib + ABBV-399
Sensitive
:
C3
MET positive
Lung Non-Small Cell Squamous Cancer
MET positive
Lung Non-Small Cell Squamous Cancer
erlotinib + ABBV-399
Sensitive: C3 – Early Trials
erlotinib + ABBV-399
Sensitive
:
C3
erlotinib + ABBV-399
Sensitive: C3 – Early Trials
erlotinib + ABBV-399
Sensitive
:
C3
MET positive
Non Small Cell Lung Cancer
MET positive
Non Small Cell Lung Cancer
erlotinib + LY2875358
Sensitive: C3 – Early Trials
erlotinib + LY2875358
Sensitive
:
C3
erlotinib + LY2875358
Sensitive: C3 – Early Trials
erlotinib + LY2875358
Sensitive
:
C3
MET positive
Gastric Cancer
MET positive
Gastric Cancer
c-MET-targeted CAR-T immunotherapy
Sensitive: D – Preclinical
c-MET-targeted CAR-T immunotherapy
Sensitive
:
D
c-MET-targeted CAR-T immunotherapy
Sensitive: D – Preclinical
c-MET-targeted CAR-T immunotherapy
Sensitive
:
D
MET positive
Gastric Cancer
MET positive
Gastric Cancer
tepotinib
Sensitive: D – Preclinical
tepotinib
Sensitive
:
D
tepotinib
Sensitive: D – Preclinical
tepotinib
Sensitive
:
D
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