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BIOMARKER:
MAP2K1 P124S
i
Other names:
MAP2K1, MAPKK1, MEK1, PRKMK1, Mitogen-activated protein kinase kinase 1
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Entrez ID:
5604
Related biomarkers:
Expression
Mutation
CNA
Others
‹
MAP2K1 mutation (9)
MAP2K1 P124L (6)
MAP2K1 C121S (3)
MAP2K1 K57T (3)
MAP2K1 P124Q (3)
BRAF V600E + MAP2K1 I111S (2)
BRAF mutation + MEK1 P124L (2)
MAP2K1 F53Y (2)
MAP2K1 G128V (2)
MAP2K1 G276W (2)
MAP2K1 Q56P (2)
MAP2K1 V154I (2)
MAP2K1 V60E (2)
BRAF mutation + MAP2K1 mutation (1)
MAP2K1 C125S (1)
MAP2K1 E203K (1)
MAP2K1 F129L (1)
MAP2K1 F53L (1)
MAP2K1 G128D + KRAS mutation (1)
MAP2K1 K57E (1)
MAP2K1 K57N (1)
MAP2K1 P124 (1)
MAP2K1 S218D + MAP2K1 S222D (1)
MAP2K1 V211D (1)
MAP2K1 V211D + BRAF mutation (1)
RAS wild-type + BRAF wild-type + MAP2K1 N57K (1)
BRAF V600E + MAP2K1 P124S (0)
MAP2K1 G128D (0)
MAP2K1 I111S (0)
MAP2K1 S218D (0)
MAP2K1 S222D (0)
MAP2K1 mutation (9)
MAP2K1 P124L (6)
MAP2K1 C121S (3)
MAP2K1 K57T (3)
MAP2K1 P124Q (3)
BRAF V600E + MAP2K1 I111S (2)
BRAF mutation + MEK1 P124L (2)
MAP2K1 F53Y (2)
MAP2K1 G128V (2)
MAP2K1 G276W (2)
MAP2K1 Q56P (2)
MAP2K1 V154I (2)
MAP2K1 V60E (2)
BRAF mutation + MAP2K1 mutation (1)
MAP2K1 C125S (1)
MAP2K1 E203K (1)
MAP2K1 F129L (1)
MAP2K1 F53L (1)
MAP2K1 G128D + KRAS mutation (1)
MAP2K1 K57E (1)
MAP2K1 K57N (1)
MAP2K1 P124 (1)
MAP2K1 S218D + MAP2K1 S222D (1)
MAP2K1 V211D (1)
MAP2K1 V211D + BRAF mutation (1)
RAS wild-type + BRAF wild-type + MAP2K1 N57K (1)
BRAF V600E + MAP2K1 P124S (0)
MAP2K1 G128D (0)
MAP2K1 I111S (0)
MAP2K1 S218D (0)
MAP2K1 S222D (0)
›
Associations
News
Trials
VERI cancer hierarchy
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MAP2K1 P124S
Melanoma
MAP2K1 P124S
Melanoma
trametinib
Sensitive: C3 – Early Trials
trametinib
Sensitive
:
C3
trametinib
Sensitive: C3 – Early Trials
trametinib
Sensitive
:
C3
MAP2K1 P124S
Melanoma
MAP2K1 P124S
Melanoma
dabrafenib
Resistant: C3 – Early Trials
dabrafenib
Resistant
:
C3
dabrafenib
Resistant: C3 – Early Trials
dabrafenib
Resistant
:
C3
MAP2K1 P124S
Melanoma
MAP2K1 P124S
Melanoma
vemurafenib
Resistant: C3 – Early Trials
vemurafenib
Resistant
:
C3
vemurafenib
Resistant: C3 – Early Trials
vemurafenib
Resistant
:
C3
MAP2K1 P124S
Melanoma
MAP2K1 P124S
Melanoma
selumetinib
Sensitive: C4 – Case Studies
selumetinib
Sensitive
:
C4
selumetinib
Sensitive: C4 – Case Studies
selumetinib
Sensitive
:
C4
MAP2K1 P124S
Melanoma
MAP2K1 P124S
Melanoma
PLX4720
Resistant: D – Preclinical
PLX4720
Resistant
:
D
PLX4720
Resistant: D – Preclinical
PLX4720
Resistant
:
D
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