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CANCER:
Malignant Pleural Mesothelioma
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Related cancers:
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Mesothelioma (88
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Mesothelioma (88
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Associations
(33)
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No biomarker
Malignant Pleural Mesothelioma
No biomarker
Malignant Pleural Mesothelioma
nivolumab + ipilimumab
Sensitive: A1 - Approval
nivolumab + ipilimumab
Sensitive
:
A1
nivolumab + ipilimumab
Sensitive: A1 - Approval
nivolumab + ipilimumab
Sensitive
:
A1
No biomarker
Malignant Pleural Mesothelioma
No biomarker
Malignant Pleural Mesothelioma
cisplatin + pemetrexed
Sensitive: A1 - Approval
cisplatin + pemetrexed
Sensitive
:
A1
cisplatin + pemetrexed
Sensitive: A1 - Approval
cisplatin + pemetrexed
Sensitive
:
A1
No biomarker
Malignant Pleural Mesothelioma
No biomarker
Malignant Pleural Mesothelioma
pemetrexed
Sensitive: A1 - Approval
pemetrexed
Sensitive
:
A1
pemetrexed
Sensitive: A1 - Approval
pemetrexed
Sensitive
:
A1
No biomarker
Malignant Pleural Mesothelioma
No biomarker
Malignant Pleural Mesothelioma
carboplatin + pemetrexed
Sensitive: A2 - Guideline
carboplatin + pemetrexed
Sensitive
:
A2
carboplatin + pemetrexed
Sensitive: A2 - Guideline
carboplatin + pemetrexed
Sensitive
:
A2
No biomarker
Malignant Pleural Mesothelioma
No biomarker
Malignant Pleural Mesothelioma
nivolumab
Sensitive: A2 - Guideline
nivolumab
Sensitive
:
A2
nivolumab
Sensitive: A2 - Guideline
nivolumab
Sensitive
:
A2
No biomarker
Malignant Pleural Mesothelioma
No biomarker
Malignant Pleural Mesothelioma
bevacizumab
Sensitive: A2 - Guideline
bevacizumab
Sensitive
:
A2
bevacizumab
Sensitive: A2 - Guideline
bevacizumab
Sensitive
:
A2
No biomarker
Malignant Pleural Mesothelioma
No biomarker
Malignant Pleural Mesothelioma
pembrolizumab
Sensitive: A2 - Guideline
pembrolizumab
Sensitive
:
A2
pembrolizumab
Sensitive: A2 - Guideline
pembrolizumab
Sensitive
:
A2
No biomarker
Malignant Pleural Mesothelioma
No biomarker
Malignant Pleural Mesothelioma
carboplatin + raltitrexed
Sensitive: A2 - Guideline
carboplatin + raltitrexed
Sensitive
:
A2
carboplatin + raltitrexed
Sensitive: A2 - Guideline
carboplatin + raltitrexed
Sensitive
:
A2
No biomarker
Malignant Pleural Mesothelioma
No biomarker
Malignant Pleural Mesothelioma
Sensitive: A2 - Guideline
Sensitive
:
A2
Sensitive: A2 - Guideline
Sensitive
:
A2
No biomarker
Malignant Pleural Mesothelioma
No biomarker
Malignant Pleural Mesothelioma
gemcitabine
Sensitive: A2 - Guideline
gemcitabine
Sensitive
:
A2
gemcitabine
Sensitive: A2 - Guideline
gemcitabine
Sensitive
:
A2
No biomarker
Malignant Pleural Mesothelioma
No biomarker
Malignant Pleural Mesothelioma
vinorelbine tartrate
Sensitive: A2 - Guideline
vinorelbine tartrate
Sensitive
:
A2
vinorelbine tartrate
Sensitive: A2 - Guideline
vinorelbine tartrate
Sensitive
:
A2
No biomarker
Malignant Pleural Mesothelioma
No biomarker
Malignant Pleural Mesothelioma
ramucirumab
Sensitive: A2 - Guideline
ramucirumab
Sensitive
:
A2
ramucirumab
Sensitive: A2 - Guideline
ramucirumab
Sensitive
:
A2
No biomarker
Malignant Pleural Mesothelioma
No biomarker
Malignant Pleural Mesothelioma
cisplatin
Sensitive: A2 - Guideline
cisplatin
Sensitive
:
A2
cisplatin
Sensitive: A2 - Guideline
cisplatin
Sensitive
:
A2
No biomarker
Malignant Pleural Mesothelioma
No biomarker
Malignant Pleural Mesothelioma
carboplatin
Sensitive: A2 - Guideline
carboplatin
Sensitive
:
A2
carboplatin
Sensitive: A2 - Guideline
carboplatin
Sensitive
:
A2
NF2 deletion
Malignant Pleural Mesothelioma
NF2 deletion
Malignant Pleural Mesothelioma
IK-930
Sensitive: B - Late Trials
IK-930
Sensitive
:
B
IK-930
Sensitive: B - Late Trials
IK-930
Sensitive
:
B
PD-L1 expression
Malignant Pleural Mesothelioma
PD-L1 expression
Malignant Pleural Mesothelioma
nivolumab
Sensitive: C1 - Off-label
nivolumab
Sensitive
:
C1
nivolumab
Sensitive: C1 - Off-label
nivolumab
Sensitive
:
C1
WT1 expression
Malignant Pleural Mesothelioma
WT1 expression
Malignant Pleural Mesothelioma
nivolumab + galinpepimut-S
Sensitive: C3 – Early Trials
nivolumab + galinpepimut-S
Sensitive
:
C3
nivolumab + galinpepimut-S
Sensitive: C3 – Early Trials
nivolumab + galinpepimut-S
Sensitive
:
C3
TMB-L
Malignant Pleural Mesothelioma
TMB-L
Malignant Pleural Mesothelioma
PD1 inhibitor
Resistant: C3 – Early Trials
PD1 inhibitor
Resistant
:
C3
PD1 inhibitor
Resistant: C3 – Early Trials
PD1 inhibitor
Resistant
:
C3
TMB-L
Malignant Pleural Mesothelioma
TMB-L
Malignant Pleural Mesothelioma
PD-L1 inhibitor
Resistant: C3 – Early Trials
PD-L1 inhibitor
Resistant
:
C3
PD-L1 inhibitor
Resistant: C3 – Early Trials
PD-L1 inhibitor
Resistant
:
C3
PD-L1 underexpression
Malignant Pleural Mesothelioma
PD-L1 underexpression
Malignant Pleural Mesothelioma
PD1 inhibitor
Resistant: C3 – Early Trials
PD1 inhibitor
Resistant
:
C3
PD1 inhibitor
Resistant: C3 – Early Trials
PD1 inhibitor
Resistant
:
C3
ERCC1 expression
Malignant Pleural Mesothelioma
ERCC1 expression
Malignant Pleural Mesothelioma
Sensitive: C3 – Early Trials
Sensitive
:
C3
Sensitive: C3 – Early Trials
Sensitive
:
C3
RRM1 expression
Malignant Pleural Mesothelioma
RRM1 expression
Malignant Pleural Mesothelioma
Sensitive: C3 – Early Trials
Sensitive
:
C3
Sensitive: C3 – Early Trials
Sensitive
:
C3
MSLN overexpression
Malignant Pleural Mesothelioma
MSLN overexpression
Malignant Pleural Mesothelioma
TC-210
Sensitive: C3 – Early Trials
TC-210
Sensitive
:
C3
TC-210
Sensitive: C3 – Early Trials
TC-210
Sensitive
:
C3
ASS1 mutation
Malignant Pleural Mesothelioma
ASS1 mutation
Malignant Pleural Mesothelioma
cisplatin + pemetrexed + pegargiminase
Sensitive: C3 – Early Trials
cisplatin + pemetrexed + pegargiminase
Sensitive
:
C3
cisplatin + pemetrexed + pegargiminase
Sensitive: C3 – Early Trials
cisplatin + pemetrexed + pegargiminase
Sensitive
:
C3
BAP1 deletion
Malignant Pleural Mesothelioma
BAP1 deletion
Malignant Pleural Mesothelioma
pemetrexed
Sensitive: C3 – Early Trials
pemetrexed
Sensitive
:
C3
pemetrexed
Sensitive: C3 – Early Trials
pemetrexed
Sensitive
:
C3
BAP1 deletion
Malignant Pleural Mesothelioma
BAP1 deletion
Malignant Pleural Mesothelioma
nivolumab + ipilimumab
Sensitive: C3 – Early Trials
nivolumab + ipilimumab
Sensitive
:
C3
nivolumab + ipilimumab
Sensitive: C3 – Early Trials
nivolumab + ipilimumab
Sensitive
:
C3
PD-L1 overexpression
Malignant Pleural Mesothelioma
PD-L1 overexpression
Malignant Pleural Mesothelioma
nivolumab
Sensitive: C4 – Case Studies
nivolumab
Sensitive
:
C4
nivolumab
Sensitive: C4 – Case Studies
nivolumab
Sensitive
:
C4
EML4-ALK I1171N + EML4-ALK L1196M
Malignant Pleural Mesothelioma
EML4-ALK I1171N + EML4-ALK L1196M
Malignant Pleural Mesothelioma
alectinib
Resistant: C4 – Case Studies
alectinib
Resistant
:
C4
alectinib
Resistant: C4 – Case Studies
alectinib
Resistant
:
C4
CD74-ROS1 fusion
Malignant Pleural Mesothelioma
CD74-ROS1 fusion
Malignant Pleural Mesothelioma
crizotinib
Sensitive: C4 – Case Studies
crizotinib
Sensitive
:
C4
crizotinib
Sensitive: C4 – Case Studies
crizotinib
Sensitive
:
C4
MTAP deletion + CDKN2A deletion + CDKN2B deletion + BAP1 deletion
Malignant Pleural Mesothelioma
MTAP deletion + CDKN2A deletion + CDKN2B deletion + BAP1 deletion
Malignant Pleural Mesothelioma
BMS‐986504
Sensitive: C4 – Case Studies
BMS‐986504
Sensitive
:
C4
BMS‐986504
Sensitive: C4 – Case Studies
BMS‐986504
Sensitive
:
C4
MTAP deletion + PIK3CA mutation
Malignant Pleural Mesothelioma
MTAP deletion + PIK3CA mutation
Malignant Pleural Mesothelioma
BMS‐986504
Sensitive: C4 – Case Studies
BMS‐986504
Sensitive
:
C4
BMS‐986504
Sensitive: C4 – Case Studies
BMS‐986504
Sensitive
:
C4
BRCA2 mutation
Malignant Pleural Mesothelioma
BRCA2 mutation
Malignant Pleural Mesothelioma
niraparib + dostarlimab-gxly
Sensitive: C4 – Case Studies
niraparib + dostarlimab-gxly
Sensitive
:
C4
niraparib + dostarlimab-gxly
Sensitive: C4 – Case Studies
niraparib + dostarlimab-gxly
Sensitive
:
C4
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