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BIOMARKER:
LYN overexpression + FLT3-ITD mutation
i
Other names:
LYN, LYN Proto-Oncogene Src Family Tyrosine Kinase, V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog, Lck/Yes-Related Novel Protein Tyrosine Kinase, Tyrosine-Protein Kinase Lyn, P53Lyn, P56Lyn, JTK8, FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
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Entrez ID:
2322
;
4067
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
NUP98-NSD1 fusion + FLT3-ITD mutation (3)
CD123 positive + FLT3-ITD mutation (1)
CSK overexpression + FLT3-ITD mutation (1)
EPHB2 overexpression + FLT3-ITD mutation (1)
FLT3 A848P + MLL-MLLT3 fusion (1)
FLT3 wild-type + TP53 mutation (1)
FLT3-ITD mutation + MLL fusion + TP53 mutation (1)
FLT3-ITD mutation + PML-RARA fusion + WT1 overexpression (1)
FLT3-ITD mutation + RIPK1 expression (1)
FLT3-ITD mutation + SKI overexpression (1)
HCK overexpression + FLT3-ITD mutation (1)
HLF overexpression + FLT3-ITD mutation (1)
KAT6A-CREBBP fusion + FLT3-TKD mutation (1)
miR-155 deletion + FLT3-ITD mutation (1)
NUP98-NSD1 fusion + FLT3-ITD mutation (3)
CD123 positive + FLT3-ITD mutation (1)
CSK overexpression + FLT3-ITD mutation (1)
EPHB2 overexpression + FLT3-ITD mutation (1)
FLT3 A848P + MLL-MLLT3 fusion (1)
FLT3 wild-type + TP53 mutation (1)
FLT3-ITD mutation + MLL fusion + TP53 mutation (1)
FLT3-ITD mutation + PML-RARA fusion + WT1 overexpression (1)
FLT3-ITD mutation + RIPK1 expression (1)
FLT3-ITD mutation + SKI overexpression (1)
HCK overexpression + FLT3-ITD mutation (1)
HLF overexpression + FLT3-ITD mutation (1)
KAT6A-CREBBP fusion + FLT3-TKD mutation (1)
miR-155 deletion + FLT3-ITD mutation (1)
›
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LYN overexpression + FLT3-ITD mutation
Acute Myelogenous Leukemia
LYN overexpression + FLT3-ITD mutation
Acute Myelogenous Leukemia
dasatinib
Resistant: D – Preclinical
dasatinib
Resistant
:
D
dasatinib
Resistant: D – Preclinical
dasatinib
Resistant
:
D
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