^
Association details:
Evidence:
Evidence Level:
Resistant: D – Preclinical
Source:
Title:

Dasatinib Inhibits FLT3/ITD and PTPN11mutated Acute Myeloid Leukemia Cells Overexpressing SRC Tyrosine Kinases

Published date:
11/06/2019
Excerpt:
We found that among FLT3/ITD AML carriers in the Beat AML cohort LYN, HCK, CSK and EPHB2 were significantly over-expressed in the dasatinib responding samples (N=27) as compared to the dasatinib resistant samples (N=35).
DOI:
10.1182/blood-2019-128016