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DRUG CLASS:
KRAS G12C inhibitor
DRUG CLASS:
KRAS G12C inhibitor
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News alerts, weekly reports and conference planners
Related drugs:
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RMC-6291 (0)
UCT-001024 (0)
VRTX126 (0)
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sotorasib (76)
adagrasib (35)
RG6330 (6)
D-1553 (6)
fulzerasib (4)
ZG19018 (4)
JAB-21822 (4)
APG-1842 (3)
ARS-1620 (2)
BI 1823911 (2)
MK-1084 (2)
JDQ443 (2)
ABSK071 (1)
AZ’8037 (1)
GEC-255 (1)
RM-029 (1)
YL-17231 (1)
D3S-001 (0)
FWD-K01 (0)
GH35 (0)
HBI-2438 (0)
HS-10370 (0)
JNJ-74699157 (0)
LY3499446 (0)
RMC-6291 (0)
UCT-001024 (0)
VRTX126 (0)
YL-15293 (0)
LY3537982 (0)
›
Associations
(152)
News
Trials
VERI cancer hierarchy
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KRAS G12C
Non Small Cell Lung Cancer
KRAS G12C
Non Small Cell Lung Cancer
sotorasib
Sensitive: A1 - Approval
sotorasib
Sensitive
:
A1
sotorasib
Sensitive: A1 - Approval
sotorasib
Sensitive
:
A1
KRAS G12C
Non Small Cell Lung Cancer
KRAS G12C
Non Small Cell Lung Cancer
adagrasib
Sensitive: A1 - Approval
adagrasib
Sensitive
:
A1
adagrasib
Sensitive: A1 - Approval
adagrasib
Sensitive
:
A1
KRAS G12C
Colorectal Cancer
KRAS G12C
Colorectal Cancer
adagrasib
Sensitive: A1 - Approval
adagrasib
Sensitive
:
A1
adagrasib
Sensitive: A1 - Approval
adagrasib
Sensitive
:
A1
KRAS G12C
Colorectal Cancer
KRAS G12C
Colorectal Cancer
cetuximab + adagrasib
Sensitive: A1 - Approval
cetuximab + adagrasib
Sensitive
:
A1
cetuximab + adagrasib
Sensitive: A1 - Approval
cetuximab + adagrasib
Sensitive
:
A1
KRAS G12C
Ampulla of Vater Carcinoma
KRAS G12C
Ampulla of Vater Carcinoma
sotorasib
Sensitive: A2 - Guideline
sotorasib
Sensitive
:
A2
sotorasib
Sensitive: A2 - Guideline
sotorasib
Sensitive
:
A2
KRAS G12C
Pancreatic Adenocarcinoma
KRAS G12C
Pancreatic Adenocarcinoma
sotorasib
Sensitive: A2 - Guideline
sotorasib
Sensitive
:
A2
sotorasib
Sensitive: A2 - Guideline
sotorasib
Sensitive
:
A2
KRAS G12C
Pancreatic Adenocarcinoma
KRAS G12C
Pancreatic Adenocarcinoma
adagrasib
Sensitive: A2 - Guideline
adagrasib
Sensitive
:
A2
adagrasib
Sensitive: A2 - Guideline
adagrasib
Sensitive
:
A2
KRAS G12C
Rectal Cancer
KRAS G12C
Rectal Cancer
panitumumab + sotorasib
Sensitive: A2 - Guideline
panitumumab + sotorasib
Sensitive
:
A2
panitumumab + sotorasib
Sensitive: A2 - Guideline
panitumumab + sotorasib
Sensitive
:
A2
KRAS G12C
Rectal Cancer
KRAS G12C
Rectal Cancer
cetuximab + sotorasib
Sensitive: A2 - Guideline
cetuximab + sotorasib
Sensitive
:
A2
cetuximab + sotorasib
Sensitive: A2 - Guideline
cetuximab + sotorasib
Sensitive
:
A2
KRAS G12C
Rectal Cancer
KRAS G12C
Rectal Cancer
panitumumab + adagrasib
Sensitive: A2 - Guideline
panitumumab + adagrasib
Sensitive
:
A2
panitumumab + adagrasib
Sensitive: A2 - Guideline
panitumumab + adagrasib
Sensitive
:
A2
KRAS G12C
Rectal Cancer
KRAS G12C
Rectal Cancer
cetuximab + adagrasib
Sensitive: A2 - Guideline
cetuximab + adagrasib
Sensitive
:
A2
cetuximab + adagrasib
Sensitive: A2 - Guideline
cetuximab + adagrasib
Sensitive
:
A2
KRAS G12C
Colon Cancer
KRAS G12C
Colon Cancer
panitumumab + sotorasib
Sensitive: A2 - Guideline
panitumumab + sotorasib
Sensitive
:
A2
panitumumab + sotorasib
Sensitive: A2 - Guideline
panitumumab + sotorasib
Sensitive
:
A2
KRAS G12C
Colon Cancer
KRAS G12C
Colon Cancer
cetuximab + sotorasib
Sensitive: A2 - Guideline
cetuximab + sotorasib
Sensitive
:
A2
cetuximab + sotorasib
Sensitive: A2 - Guideline
cetuximab + sotorasib
Sensitive
:
A2
KRAS G12C
Colon Cancer
KRAS G12C
Colon Cancer
cetuximab + adagrasib
Sensitive: A2 - Guideline
cetuximab + adagrasib
Sensitive
:
A2
cetuximab + adagrasib
Sensitive: A2 - Guideline
cetuximab + adagrasib
Sensitive
:
A2
KRAS G12C
Colon Cancer
KRAS G12C
Colon Cancer
panitumumab + adagrasib
Sensitive: A2 - Guideline
panitumumab + adagrasib
Sensitive
:
A2
panitumumab + adagrasib
Sensitive: A2 - Guideline
panitumumab + adagrasib
Sensitive
:
A2
KRAS G12C
Ampulla of Vater Carcinoma
KRAS G12C
Ampulla of Vater Carcinoma
adagrasib
Sensitive: A2 - Guideline
adagrasib
Sensitive
:
A2
adagrasib
Sensitive: A2 - Guideline
adagrasib
Sensitive
:
A2
KRAS G12C
Colorectal Cancer
KRAS G12C
Colorectal Cancer
panitumumab + sotorasib
Sensitive: B - Late Trials
panitumumab + sotorasib
Sensitive
:
B
panitumumab + sotorasib
Sensitive: B - Late Trials
panitumumab + sotorasib
Sensitive
:
B
KRAS G12C + KEAP1 mutation
Non Small Cell Lung Cancer
KRAS G12C + KEAP1 mutation
Non Small Cell Lung Cancer
sotorasib
Resistant: B - Late Trials
sotorasib
Resistant
:
B
sotorasib
Resistant: B - Late Trials
sotorasib
Resistant
:
B
KRAS G12C
Non Small Cell Lung Cancer
KRAS G12C
Non Small Cell Lung Cancer
sotorasib + BMS-986466
Sensitive: B - Late Trials
sotorasib + BMS-986466
Sensitive
:
B
sotorasib + BMS-986466
Sensitive: B - Late Trials
sotorasib + BMS-986466
Sensitive
:
B
KRAS G12C + STK11 mutation
Non Small Cell Lung Cancer
KRAS G12C + STK11 mutation
Non Small Cell Lung Cancer
sotorasib
Sensitive: B - Late Trials
sotorasib
Sensitive
:
B
sotorasib
Sensitive: B - Late Trials
sotorasib
Sensitive
:
B
KRAS G12C + TP53 mutation
Non Small Cell Lung Cancer
KRAS G12C + TP53 mutation
Non Small Cell Lung Cancer
sotorasib
Sensitive: B - Late Trials
sotorasib
Sensitive
:
B
sotorasib
Sensitive: B - Late Trials
sotorasib
Sensitive
:
B
KRAS G12C
Pancreatic Cancer
KRAS G12C
Pancreatic Cancer
JAB-21822
Sensitive: B - Late Trials
JAB-21822
Sensitive
:
B
JAB-21822
Sensitive: B - Late Trials
JAB-21822
Sensitive
:
B
KRAS G12C
Pancreatic Cancer
KRAS G12C
Pancreatic Cancer
sotorasib
Sensitive: C1 - Off-label
sotorasib
Sensitive
:
C1
sotorasib
Sensitive: C1 - Off-label
sotorasib
Sensitive
:
C1
KRAS G12C
Cholangiocarcinoma
KRAS G12C
Cholangiocarcinoma
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
KRAS G12C
Ovarian Cancer
KRAS G12C
Ovarian Cancer
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
KRAS G12C
Pancreatic Cancer
KRAS G12C
Pancreatic Cancer
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
KRAS G12C
Endometrial Cancer
KRAS G12C
Endometrial Cancer
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
KRAS G12C
Melanoma
KRAS G12C
Melanoma
sotorasib
Sensitive: C1 - Off-label
sotorasib
Sensitive
:
C1
sotorasib
Sensitive: C1 - Off-label
sotorasib
Sensitive
:
C1
KRAS G12C
Endometrial Cancer
KRAS G12C
Endometrial Cancer
sotorasib
Sensitive: C1 - Off-label
sotorasib
Sensitive
:
C1
sotorasib
Sensitive: C1 - Off-label
sotorasib
Sensitive
:
C1
KRAS G12C
Colorectal Cancer
KRAS G12C
Colorectal Cancer
sotorasib
Sensitive: C1 - Off-label
sotorasib
Sensitive
:
C1
sotorasib
Sensitive: C1 - Off-label
sotorasib
Sensitive
:
C1
KRAS G12C
Gastrointestinal Cancer
KRAS G12C
Gastrointestinal Cancer
sotorasib
Sensitive: C1 - Off-label
sotorasib
Sensitive
:
C1
sotorasib
Sensitive: C1 - Off-label
sotorasib
Sensitive
:
C1
KRAS G12C
Gastrointestinal Cancer
KRAS G12C
Gastrointestinal Cancer
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
^
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