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BIOMARKER:
KIT N822K
i
Other names:
KIT, C-Kit, CD117, PBT, SCFR, Stem Cell Factor Receptor, V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
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Entrez ID:
3815
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
Chr t(8;21) + KIT mutation (4)
Chr t(8;21)(q22;q22) + RUNX1-RUNX1T1 fusion + KIT exon 17 mutation + CSF3R mutation (4)
Chr t(8;21)(q22;q22) + RUNX1-RUNX1T1 fusion + KIT exon 17 mutation (3)
KIT P577del + KIT W557Lfs*5 + KIT Y823D (2)
Chr inv(16)t(16;16) + KIT mutation (1)
KIT wild-type + SDHB deletion (1)
RUNX1-RUNX1T1 fusion + KIT D816 (1)
Chr t(8;21) + KIT mutation (4)
Chr t(8;21)(q22;q22) + RUNX1-RUNX1T1 fusion + KIT exon 17 mutation + CSF3R mutation (4)
Chr t(8;21)(q22;q22) + RUNX1-RUNX1T1 fusion + KIT exon 17 mutation (3)
KIT P577del + KIT W557Lfs*5 + KIT Y823D (2)
Chr inv(16)t(16;16) + KIT mutation (1)
KIT wild-type + SDHB deletion (1)
RUNX1-RUNX1T1 fusion + KIT D816 (1)
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Associations
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Trials
VERI cancer hierarchy
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KIT N822K
Gastrointestinal Stromal Tumor
KIT N822K
Gastrointestinal Stromal Tumor
dasatinib
Sensitive: C3 – Early Trials
dasatinib
Sensitive
:
C3
dasatinib
Sensitive: C3 – Early Trials
dasatinib
Sensitive
:
C3
KIT N822K
Gastrointestinal Stromal Tumor
KIT N822K
Gastrointestinal Stromal Tumor
imatinib
Sensitive: C3 – Early Trials
imatinib
Sensitive
:
C3
imatinib
Sensitive: C3 – Early Trials
imatinib
Sensitive
:
C3
KIT N822K
Acute Myelogenous Leukemia
KIT N822K
Acute Myelogenous Leukemia
imatinib
Sensitive: D – Preclinical
imatinib
Sensitive
:
D
imatinib
Sensitive: D – Preclinical
imatinib
Sensitive
:
D
KIT N822K
Acute Myelogenous Leukemia
KIT N822K
Acute Myelogenous Leukemia
GB-103
Resistant: D – Preclinical
GB-103
Resistant
:
D
GB-103
Resistant: D – Preclinical
GB-103
Resistant
:
D
KIT N822K
Acute Myelogenous Leukemia
KIT N822K
Acute Myelogenous Leukemia
sorafenib
Resistant: D – Preclinical
sorafenib
Resistant
:
D
sorafenib
Resistant: D – Preclinical
sorafenib
Resistant
:
D
KIT N822K
Acute Myelogenous Leukemia
KIT N822K
Acute Myelogenous Leukemia
ponatinib
Sensitive: D – Preclinical
ponatinib
Sensitive
:
D
ponatinib
Sensitive: D – Preclinical
ponatinib
Sensitive
:
D
KIT N822K
Acute Myelogenous Leukemia
KIT N822K
Acute Myelogenous Leukemia
dasatinib
Sensitive: D – Preclinical
dasatinib
Sensitive
:
D
dasatinib
Sensitive: D – Preclinical
dasatinib
Sensitive
:
D
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