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DRUG:
Inlyta (axitinib)
i
Other names:
AG-13,736, AG-013736, AG013736, AG 013736, AG 13736
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Associations
(34)
News
Trials
Company:
Pfizer
Drug class:
VEGFR inhibitor
Related drugs:
‹
sunitinib (139)
lenvatinib (90)
fruquintinib (24)
cediranib (9)
TKI258 (9)
surufatinib (7)
MGCD265 (4)
E 3810 (4)
OMP-305B83 (3)
ABT-869 (2)
DC101 (1)
vorolanib (1)
CS 2164 (1)
KD019 (1)
BMS690514 (0)
CVX-241 (0)
ESK981 (0)
adAptVEGF-C adenoviral vector (0)
SU 14813 (0)
SYHA1813 (0)
VEGFR1-1084 (0)
ABT-165 (0)
IMC-18F1 (0)
ABT348 (0)
PI-88 (0)
SU5416 (0)
GS 6624 (0)
BAY 57- 9352 (0)
RG7221 (0)
PTK787 (0)
sunitinib (139)
lenvatinib (90)
fruquintinib (24)
cediranib (9)
TKI258 (9)
surufatinib (7)
MGCD265 (4)
E 3810 (4)
OMP-305B83 (3)
ABT-869 (2)
DC101 (1)
vorolanib (1)
CS 2164 (1)
KD019 (1)
BMS690514 (0)
CVX-241 (0)
ESK981 (0)
adAptVEGF-C adenoviral vector (0)
SU 14813 (0)
SYHA1813 (0)
VEGFR1-1084 (0)
ABT-165 (0)
IMC-18F1 (0)
ABT348 (0)
PI-88 (0)
SU5416 (0)
GS 6624 (0)
BAY 57- 9352 (0)
RG7221 (0)
PTK787 (0)
›
Associations
(34)
News
Trials
VERI cancer hierarchy
Reset Filters
No biomarker
Renal Cell Carcinoma
No biomarker
Renal Cell Carcinoma
avelumab + axitinib
Sensitive: A1 - Approval
avelumab + axitinib
Sensitive
:
A1
avelumab + axitinib
Sensitive: A1 - Approval
avelumab + axitinib
Sensitive
:
A1
No biomarker
Renal Cell Carcinoma
No biomarker
Renal Cell Carcinoma
pembrolizumab + axitinib
Sensitive: A1 - Approval
pembrolizumab + axitinib
Sensitive
:
A1
pembrolizumab + axitinib
Sensitive: A1 - Approval
pembrolizumab + axitinib
Sensitive
:
A1
No biomarker
Renal Cell Carcinoma
No biomarker
Renal Cell Carcinoma
axitinib
Sensitive: A1 - Approval
axitinib
Sensitive
:
A1
axitinib
Sensitive: A1 - Approval
axitinib
Sensitive
:
A1
No biomarker
Clear Cell Renal Cell Carcinoma
No biomarker
Clear Cell Renal Cell Carcinoma
avelumab + axitinib
Sensitive: A2 - Guideline
avelumab + axitinib
Sensitive
:
A2
avelumab + axitinib
Sensitive: A2 - Guideline
avelumab + axitinib
Sensitive
:
A2
No biomarker
Clear Cell Renal Cell Carcinoma
No biomarker
Clear Cell Renal Cell Carcinoma
pembrolizumab + axitinib
Sensitive: A2 - Guideline
pembrolizumab + axitinib
Sensitive
:
A2
pembrolizumab + axitinib
Sensitive: A2 - Guideline
pembrolizumab + axitinib
Sensitive
:
A2
No biomarker
Clear Cell Renal Cell Carcinoma
No biomarker
Clear Cell Renal Cell Carcinoma
axitinib
Sensitive: A2 - Guideline
axitinib
Sensitive
:
A2
axitinib
Sensitive: A2 - Guideline
axitinib
Sensitive
:
A2
No biomarker
Soft Tissue Sarcoma
No biomarker
Soft Tissue Sarcoma
pembrolizumab + axitinib
Sensitive: A2 - Guideline
pembrolizumab + axitinib
Sensitive
:
A2
pembrolizumab + axitinib
Sensitive: A2 - Guideline
pembrolizumab + axitinib
Sensitive
:
A2
No biomarker
Kidney Cancer
No biomarker
Kidney Cancer
pembrolizumab + axitinib
Sensitive: A2 - Guideline
pembrolizumab + axitinib
Sensitive
:
A2
pembrolizumab + axitinib
Sensitive: A2 - Guideline
pembrolizumab + axitinib
Sensitive
:
A2
No biomarker
Kidney Cancer
No biomarker
Kidney Cancer
axitinib
Sensitive: A2 - Guideline
axitinib
Sensitive
:
A2
axitinib
Sensitive: A2 - Guideline
axitinib
Sensitive
:
A2
No biomarker
Kidney Cancer
No biomarker
Kidney Cancer
avelumab + axitinib
Sensitive: A2 - Guideline
avelumab + axitinib
Sensitive
:
A2
avelumab + axitinib
Sensitive: A2 - Guideline
avelumab + axitinib
Sensitive
:
A2
PD-L1 expression
Clear Cell Renal Cell Carcinoma
PD-L1 expression
Clear Cell Renal Cell Carcinoma
pembrolizumab + axitinib
Sensitive: B - Late Trials
pembrolizumab + axitinib
Sensitive
:
B
pembrolizumab + axitinib
Sensitive: B - Late Trials
pembrolizumab + axitinib
Sensitive
:
B
PD-L1 expression
Renal Cell Carcinoma
PD-L1 expression
Renal Cell Carcinoma
avelumab + axitinib
Sensitive: B - Late Trials
avelumab + axitinib
Sensitive
:
B
avelumab + axitinib
Sensitive: B - Late Trials
avelumab + axitinib
Sensitive
:
B
PD-L1 expression
Renal Cell Carcinoma
PD-L1 expression
Renal Cell Carcinoma
pembrolizumab + axitinib
Sensitive: B - Late Trials
pembrolizumab + axitinib
Sensitive
:
B
pembrolizumab + axitinib
Sensitive: B - Late Trials
pembrolizumab + axitinib
Sensitive
:
B
HLA-A*03
Renal Cell Carcinoma
HLA-A*03
Renal Cell Carcinoma
avelumab + axitinib
Resistant: B - Late Trials
avelumab + axitinib
Resistant
:
B
avelumab + axitinib
Resistant: B - Late Trials
avelumab + axitinib
Resistant
:
B
No biomarker
Renal Cell Carcinoma
No biomarker
Renal Cell Carcinoma
toripalimab-tpzi + axitinib
Sensitive: B - Late Trials
toripalimab-tpzi + axitinib
Sensitive
:
B
toripalimab-tpzi + axitinib
Sensitive: B - Late Trials
toripalimab-tpzi + axitinib
Sensitive
:
B
PD-L1 expression
Melanoma
PD-L1 expression
Melanoma
toripalimab-tpzi + axitinib
Sensitive: C2 – Inclusion Criteria
toripalimab-tpzi + axitinib
Sensitive
:
C2
toripalimab-tpzi + axitinib
Sensitive: C2 – Inclusion Criteria
toripalimab-tpzi + axitinib
Sensitive
:
C2
PAI1 elevation
Renal Cell Carcinoma
PAI1 elevation
Renal Cell Carcinoma
axitinib
Resistant: C3 – Early Trials
axitinib
Resistant
:
C3
axitinib
Resistant: C3 – Early Trials
axitinib
Resistant
:
C3
CEACAM1 overexpression
Renal Cell Carcinoma
CEACAM1 overexpression
Renal Cell Carcinoma
pembrolizumab + axitinib
Sensitive: C3 – Early Trials
pembrolizumab + axitinib
Sensitive
:
C3
pembrolizumab + axitinib
Sensitive: C3 – Early Trials
pembrolizumab + axitinib
Sensitive
:
C3
CXCL10 overexpression
Renal Cell Carcinoma
CXCL10 overexpression
Renal Cell Carcinoma
pembrolizumab + axitinib
Sensitive: C3 – Early Trials
pembrolizumab + axitinib
Sensitive
:
C3
pembrolizumab + axitinib
Sensitive: C3 – Early Trials
pembrolizumab + axitinib
Sensitive
:
C3
TMB-L
Non Small Cell Lung Cancer
TMB-L
Non Small Cell Lung Cancer
palbociclib + avelumab + axitinib
Sensitive: C3 – Early Trials
palbociclib + avelumab + axitinib
Sensitive
:
C3
palbociclib + avelumab + axitinib
Sensitive: C3 – Early Trials
palbociclib + avelumab + axitinib
Sensitive
:
C3
IL6 elevation
Renal Cell Carcinoma
IL6 elevation
Renal Cell Carcinoma
pembrolizumab + axitinib
Resistant: C3 – Early Trials
pembrolizumab + axitinib
Resistant
:
C3
pembrolizumab + axitinib
Resistant: C3 – Early Trials
pembrolizumab + axitinib
Resistant
:
C3
FH deletion
Renal Cell Carcinoma
FH deletion
Renal Cell Carcinoma
sintilimab + axitinib
Sensitive: C3 – Early Trials
sintilimab + axitinib
Sensitive
:
C3
sintilimab + axitinib
Sensitive: C3 – Early Trials
sintilimab + axitinib
Sensitive
:
C3
TMB-H
Urothelial Cancer
TMB-H
Urothelial Cancer
avelumab + axitinib
Sensitive: C3 – Early Trials
avelumab + axitinib
Sensitive
:
C3
avelumab + axitinib
Sensitive: C3 – Early Trials
avelumab + axitinib
Sensitive
:
C3
TMB-L
Non Small Cell Lung Cancer
TMB-L
Non Small Cell Lung Cancer
avelumab + axitinib
Sensitive: C3 – Early Trials
avelumab + axitinib
Sensitive
:
C3
avelumab + axitinib
Sensitive: C3 – Early Trials
avelumab + axitinib
Sensitive
:
C3
LDH elevation
Renal Cell Carcinoma
LDH elevation
Renal Cell Carcinoma
axitinib
Resistant: C3 – Early Trials
axitinib
Resistant
:
C3
axitinib
Resistant: C3 – Early Trials
axitinib
Resistant
:
C3
BCR-ABL1 T315L
Acute Lymphocytic Leukemia
BCR-ABL1 T315L
Acute Lymphocytic Leukemia
axitinib
Sensitive: C4 – Case Studies
axitinib
Sensitive
:
C4
axitinib
Sensitive: C4 – Case Studies
axitinib
Sensitive
:
C4
PBRM1 mutation + SETD2 mutation
Renal Cell Carcinoma
PBRM1 mutation + SETD2 mutation
Renal Cell Carcinoma
temsirolimus + axitinib
Sensitive: C4 – Case Studies
temsirolimus + axitinib
Sensitive
:
C4
temsirolimus + axitinib
Sensitive: C4 – Case Studies
temsirolimus + axitinib
Sensitive
:
C4
BCR-ABL1 T315I
Chronic Myeloid Leukemia
BCR-ABL1 T315I
Chronic Myeloid Leukemia
axitinib
Sensitive: C4 – Case Studies
axitinib
Sensitive
:
C4
axitinib
Sensitive: C4 – Case Studies
axitinib
Sensitive
:
C4
BCR-ABL1 T315I
Chronic Myeloid Leukemia
BCR-ABL1 T315I
Chronic Myeloid Leukemia
dasatinib + axitinib
Sensitive: C4 – Case Studies
dasatinib + axitinib
Sensitive
:
C4
dasatinib + axitinib
Sensitive: C4 – Case Studies
dasatinib + axitinib
Sensitive
:
C4
SETD2 mutation + TP53 mutation
Renal Cell Carcinoma
SETD2 mutation + TP53 mutation
Renal Cell Carcinoma
pembrolizumab + axitinib
Sensitive: C4 – Case Studies
pembrolizumab + axitinib
Sensitive
:
C4
pembrolizumab + axitinib
Sensitive: C4 – Case Studies
pembrolizumab + axitinib
Sensitive
:
C4
CCNE1 amplification
Renal Cell Carcinoma
CCNE1 amplification
Renal Cell Carcinoma
axitinib
Resistant: D – Preclinical
axitinib
Resistant
:
D
axitinib
Resistant: D – Preclinical
axitinib
Resistant
:
D
BRAF V600E
Thyroid Gland Anaplastic Carcinoma
BRAF V600E
Thyroid Gland Anaplastic Carcinoma
PLX4720 + axitinib
Sensitive: D – Preclinical
PLX4720 + axitinib
Sensitive
:
D
PLX4720 + axitinib
Sensitive: D – Preclinical
PLX4720 + axitinib
Sensitive
:
D
^
^
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