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DRUG:

Truseltiq (infigratinib)

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Company:

BridgeBio, Juniper Bio, Kyowa Kirin, LianBio, Novartis, Pfizer, Xediton Pharma

Drug class:

FGFR inhibitor

Related drugs:

FGFR2 rearrangement	Cholangiocarcinoma	FGFR2 rearrangement	Cholangiocarcinoma	infigratinib Sensitive: A1 - Approval infigratinib Sensitive : A1	infigratinib Sensitive: A1 - Approval infigratinib Sensitive : A1
FGFR2 fusion	Cholangiocarcinoma	FGFR2 fusion	Cholangiocarcinoma	infigratinib Sensitive: A1 - Approval infigratinib Sensitive : A1	infigratinib Sensitive: A1 - Approval infigratinib Sensitive : A1
No biomarker	Cholangiocarcinoma	No biomarker	Cholangiocarcinoma	infigratinib Sensitive: B - Late Trials infigratinib Sensitive : B	infigratinib Sensitive: B - Late Trials infigratinib Sensitive : B
FGFR2 fusion	Solid Tumor	FGFR2 fusion	Solid Tumor	infigratinib Sensitive: C1 - Off-label infigratinib Sensitive : C1	infigratinib Sensitive: C1 - Off-label infigratinib Sensitive : C1
FGFR2 fusion	Glioma	FGFR2 fusion	Glioma	infigratinib Sensitive: C1 - Off-label infigratinib Sensitive : C1	infigratinib Sensitive: C1 - Off-label infigratinib Sensitive : C1
FGFR2 fusion	Gastric Cancer	FGFR2 fusion	Gastric Cancer	infigratinib Sensitive: C1 - Off-label infigratinib Sensitive : C1	infigratinib Sensitive: C1 - Off-label infigratinib Sensitive : C1
FGFR2 fusion	Breast Cancer	FGFR2 fusion	Breast Cancer	infigratinib Sensitive: C1 - Off-label infigratinib Sensitive : C1	infigratinib Sensitive: C1 - Off-label infigratinib Sensitive : C1
FGFR2 fusion	Hepatocellular Cancer	FGFR2 fusion	Hepatocellular Cancer	infigratinib Sensitive: C1 - Off-label infigratinib Sensitive : C1	infigratinib Sensitive: C1 - Off-label infigratinib Sensitive : C1
FGFR1 amplification	Lung Non-Small Cell Squamous Cancer	FGFR1 amplification	Lung Non-Small Cell Squamous Cancer	infigratinib Sensitive: C2 – Inclusion Criteria infigratinib Sensitive : C2	infigratinib Sensitive: C2 – Inclusion Criteria infigratinib Sensitive : C2
FGFR2 mutation	Cholangiocarcinoma	FGFR2 mutation	Cholangiocarcinoma	infigratinib Sensitive: C2 – Inclusion Criteria infigratinib Sensitive : C2	infigratinib Sensitive: C2 – Inclusion Criteria infigratinib Sensitive : C2
FGFR3 mutation	Urothelial Cancer	FGFR3 mutation	Urothelial Cancer	infigratinib Sensitive: C2 – Inclusion Criteria infigratinib Sensitive : C2	infigratinib Sensitive: C2 – Inclusion Criteria infigratinib Sensitive : C2
FGFR3 mutation	Bladder Cancer	FGFR3 mutation	Bladder Cancer	infigratinib Sensitive: C2 – Inclusion Criteria infigratinib Sensitive : C2	infigratinib Sensitive: C2 – Inclusion Criteria infigratinib Sensitive : C2