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GENE:

IL7R (Interleukin 7 Receptor)

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FusionPlex™ Pan-Heme panel

OncoGuide™ NCC Oncopanel System

FusionPlex™ Pan-Heme panel

OncoGuide™ NCC Oncopanel System

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IL7R mutation	Childhood B Acute Lymphoblastic Leukemia	IL7R mutation	Childhood B Acute Lymphoblastic Leukemia	ruxolitinib Sensitive: A2 - Guideline ruxolitinib Sensitive : A2	ruxolitinib Sensitive: A2 - Guideline ruxolitinib Sensitive : A2
IL7R mutation	Acute Lymphocytic Leukemia	IL7R mutation	Acute Lymphocytic Leukemia	ruxolitinib Sensitive: C2 – Inclusion Criteria ruxolitinib Sensitive : C2	ruxolitinib Sensitive: C2 – Inclusion Criteria ruxolitinib Sensitive : C2
IL7R overexpression	Multiple Myeloma	IL7R overexpression	Multiple Myeloma	bb21217 Sensitive: C3 – Early Trials bb21217 Sensitive : C3	bb21217 Sensitive: C3 – Early Trials bb21217 Sensitive : C3
IL7R-BCL2 fusion	Sarcoma	IL7R-BCL2 fusion	Sarcoma	venetoclax Resistant: C3 – Early Trials venetoclax Resistant : C3	venetoclax Resistant: C3 – Early Trials venetoclax Resistant : C3
IL7R mutation	B Acute Lymphoblastic Leukemia	IL7R mutation	B Acute Lymphoblastic Leukemia	Sphingosine kinase inhibitor Sensitive: D – Preclinical Sphingosine kinase inhibitor Sensitive : D	Sphingosine kinase inhibitor Sensitive: D – Preclinical Sphingosine kinase inhibitor Sensitive : D
IL7R expression	B Acute Lymphoblastic Leukemia	IL7R expression	B Acute Lymphoblastic Leukemia	OSE-127 Sensitive: D – Preclinical OSE-127 Sensitive : D	OSE-127 Sensitive: D – Preclinical OSE-127 Sensitive : D