^
Association details:
| Biomarker: | IL7R mutation |
|---|---|
| Cancer: | B Acute Lymphoblastic Leukemia |
| Drug Class: | Sphingosine kinase inhibitor |
| Direction: | Sensitive |
Evidence:
Source:
Title:
IL7R MUTATIONAL ACTIVATION CAN INITIATE PH-LIKE AND PAX5 P80R PRECURSOR B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Published date:
05/12/2021
Excerpt:
We demonstrate that 2 distinct new generation sphingosine kinase inhibitors are effective against mutant IL7R mouse B-ALLs both in vitro and in vivo.
