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BIOMARKER:
IKZF1 mutation
i
Other names:
IKZF1, IKAROS Family Zinc Finger 1, Zinc Finger Protein Subfamily 1A 1 (Ikaros), Protein Phosphatase 1 Regulatory Subunit 92, Ikaros Family Zinc Finger Protein 1, Lymphoid Transcription Factor LyF-1, DNA-Binding Protein Ikaros, ZNFN1A1, IKAROS, LYF1, IK1, IKAROS Family Zinc Finger 1 (Ikaros), CLL-Associated Antigen KW-6, Hs.54452, PPP1R92, PRO0758, CVID13, LyF-1
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Entrez ID:
10320
Related biomarkers:
Expression
Mutation
CNA
‹
IKZF1 deletion (5)
IKZF1 deletion + CDKN2A deletion (2)
IKZF1 deletion + CDKN2B deletion (2)
IKZF1 deletion + IKZF3 deletion (1)
IKZF1 deletion + PAX5 deletion (1)
IKZF1 deletion + VPREB1 deletion (1)
IKZF1 deletion + CDKN2A deletion + CDKN2B deletion + PAX5 deletion (0)
IKZF1 deletion (5)
IKZF1 deletion + CDKN2A deletion (2)
IKZF1 deletion + CDKN2B deletion (2)
IKZF1 deletion + IKZF3 deletion (1)
IKZF1 deletion + PAX5 deletion (1)
IKZF1 deletion + VPREB1 deletion (1)
IKZF1 deletion + CDKN2A deletion + CDKN2B deletion + PAX5 deletion (0)
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Associations
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Trials
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IKZF1 mutation
B Acute Lymphoblastic Leukemia
IKZF1 mutation
B Acute Lymphoblastic Leukemia
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
IKZF1 mutation
Acute Lymphocytic Leukemia
IKZF1 mutation
Acute Lymphocytic Leukemia
blinatumomab
Sensitive: C3 – Early Trials
blinatumomab
Sensitive
:
C3
blinatumomab
Sensitive: C3 – Early Trials
blinatumomab
Sensitive
:
C3
IKZF1 mutation
Chronic Myeloid Leukemia
IKZF1 mutation
Chronic Myeloid Leukemia
Tyrosine kinase inhibitor
Resistant: C3 – Early Trials
Tyrosine kinase inhibitor
Resistant
:
C3
Tyrosine kinase inhibitor
Resistant: C3 – Early Trials
Tyrosine kinase inhibitor
Resistant
:
C3
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