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BIOMARKER:
IKZF1 deletion
i
Other names:
IKZF1, IKAROS Family Zinc Finger 1, Zinc Finger Protein Subfamily 1A 1 (Ikaros), Protein Phosphatase 1 Regulatory Subunit 92, Ikaros Family Zinc Finger Protein 1, Lymphoid Transcription Factor LyF-1, DNA-Binding Protein Ikaros, ZNFN1A1, IKAROS, LYF1, IK1, IKAROS Family Zinc Finger 1 (Ikaros), CLL-Associated Antigen KW-6, Hs.54452, PPP1R92, PRO0758, CVID13, LyF-1
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Entrez ID:
10320
Related biomarkers:
Expression
Mutation
CNA
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Associations
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Trials
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IKZF1 deletion
Acute Myelogenous Leukemia
IKZF1 deletion
Acute Myelogenous Leukemia
ponatinib
Resistant: C3 – Early Trials
ponatinib
Resistant
:
C3
ponatinib
Resistant: C3 – Early Trials
ponatinib
Resistant
:
C3
IKZF1 deletion
Acute Lymphocytic Leukemia
IKZF1 deletion
Acute Lymphocytic Leukemia
dasatinib + blinatumomab
Resistant: C3 – Early Trials
dasatinib + blinatumomab
Resistant
:
C3
dasatinib + blinatumomab
Resistant: C3 – Early Trials
dasatinib + blinatumomab
Resistant
:
C3
IKZF1 deletion
Acute Lymphocytic Leukemia
IKZF1 deletion
Acute Lymphocytic Leukemia
dasatinib
Sensitive: C3 – Early Trials
dasatinib
Sensitive
:
C3
dasatinib
Sensitive: C3 – Early Trials
dasatinib
Sensitive
:
C3
IKZF1 deletion
B Acute Lymphoblastic Leukemia
IKZF1 deletion
B Acute Lymphoblastic Leukemia
CD19-targeted CAR-T immunotherapy
Resistant: C3 – Early Trials
CD19-targeted CAR-T immunotherapy
Resistant
:
C3
CD19-targeted CAR-T immunotherapy
Resistant: C3 – Early Trials
CD19-targeted CAR-T immunotherapy
Resistant
:
C3
IKZF1 deletion
Acute Lymphocytic Leukemia
IKZF1 deletion
Acute Lymphocytic Leukemia
cytarabine
Resistant: D – Preclinical
cytarabine
Resistant
:
D
cytarabine
Resistant: D – Preclinical
cytarabine
Resistant
:
D
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