^
Association details:
| Biomarker: | IGF1 elevation |
|---|---|
| Cancer: | Ewing Sarcoma |
| Drug: | figitumumab (CP-751,871) (IGF-1R inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Preliminary efficacy of the anti-insulin-like growth factor type 1 receptor antibody figitumumab in patients with refractory Ewing sarcoma
Excerpt:
A late improvement of PFS in patients with elevated free IGF-1 was observed (log-rank P < .001) but the effect on median PFS was minor.
DOI:
10.1200/JCO.2010.33.0670
