^
Association details:
| Biomarker: | IDH2 mutation |
|---|---|
| Cancer: | Glioblastoma |
| Drug: | Temodex (temozolomide gel) (DNA synthesis inhibitor, Alkylating agent) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
IDH mutations predict longer survival and response to temozolomide in secondary glioblastoma
Excerpt:
Progression‐free survival...IDH mutation...MGMT promoter methylation...and 1p19q codeletion were associated with increased PFS...IDH mutation, MGMT promoter methylation, and 1p19q codeletion were strongly correlated with increased OS (P<0.001, P<0.001, P=0.003, respectively)...
DOI:
10.1111/j.1349-7006.2011.02134.x
