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BIOMARKER:

IDH2 mutation + Chr del(1p) + Chr del(19q)

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Other names: IDH2, Isocitrate Dehydrogenase (NADP(+)) 2, Isocitrate Dehydrogenase (NADP(+)) 2, Mitochondrial, Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial, Isocitrate Dehydrogenase [NADP], Mitochondrial, Oxalosuccinate Decarboxylase, NADP(+)-Specific ICDH, ICD-M, IDH, IDP, MNADP-IDH, D2HGA2, IDHM, IDPM
Entrez ID:
Related biomarkers:
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Trials
IDH2 mutation + Chr del(1p) + Chr del(19q)
Oligodendroglioma
temozolomide
Sensitive: A2 - Guideline
IDH2 mutation + Chr del(1p) + Chr del(19q)
Oligodendroglioma
bevacizumab
Sensitive: A2 - Guideline
IDH2 mutation + Chr del(1p) + Chr del(19q)
Oligodendroglioma
carmustine
Sensitive: A2 - Guideline
IDH2 mutation + Chr del(1p) + Chr del(19q)
Oligodendroglioma
lomustine
Sensitive: A2 - Guideline
IDH2 mutation + Chr del(1p) + Chr del(19q)
Oligodendroglioma
PCV
Sensitive: A2 - Guideline
IDH2 mutation + Chr del(1p) + Chr del(19q)
Oligodendroglioma
cisplatin
Sensitive: A2 - Guideline
IDH2 mutation + Chr del(1p) + Chr del(19q)
Oligodendroglioma
carboplatin
Sensitive: A2 - Guideline
IDH2 mutation + Chr del(1p) + Chr del(19q)
Oligodendroglioma
etoposide IV
Sensitive: A2 - Guideline
IDH2 mutation + Chr del(1p) + Chr del(19q)
Glioma
nivolumab
Sensitive: C3 – Early Trials