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Association details:
Biomarker:
IDH2 mutation + Chr del(1p) + Chr del(19q)
Cancer:
Oligodendroglioma
Drug:
temozolomide
(
DNA synthesis inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
NCCN
Excerpt:
ADULT GLIOMA: OLIGODENDROGLIOMA (IDH-MUTANT, 1p19q CODELETED)...Adjuvant Treatment WHO grade 2, KPS ≥60....Preferred Regimens...RT + adjuvant TMZ...RT + concurrent and adjuvant TMZ....Other Recommended Regimens...TMZ
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