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Association details:
Biomarker:
IDH1 mutation
Cancer:
Chronic Myelomonocytic Leukemia
Drug:
Venclexta (venetoclax)
(
Bcl2 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
ASH 2020
Title:
2189 Activity of Venetoclax-Based Therapy in CMML and CMML with Blast Transformation
Published date:
11/04/2020
Excerpt:
We retrospectively reviewed pts with CMML, both with and without BT, treated with VEN-based therapy…Two pts had IDH mutations and both achieved CR.
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