^
No biomarker
CMML
azacitidine
Sensitive
:
A1
No biomarker
CMML
decitabine/cedazuridine
Sensitive
:
A1
RUNX1 mutation
CMML
venetoclax
Sensitive
:
C2
IDH2 mutation
CMML
venetoclax
Sensitive
:
C3
IDH1 mutation
CMML
venetoclax
Sensitive
:
C3
NPM1 mutation
CMML
venetoclax
Sensitive
:
C3
NRAS mutation
CMML
KB003
Sensitive
:
C3
NRAS G12D
CMML
trametinib
Resistant
:
C4
RANBP2-ALK fusion
CMML
cytarabine + daunorubicin
Sensitive
:
C4
CBL C384Y
CMML
dasatinib
Sensitive
:
D
KDM6B overexpression + TET2 deletion
CMML
GSKJ4
Sensitive
:
D
KRAS G12D
CMML
trametinib
Resistant
:
D
NRAS G12D
CMML
selumetinib
Resistant
:
D
KRAS G12D
CMML
selumetinib
Resistant
:
D
CBL mutation
CMML
dasatinib
Sensitive
:
D
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