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BIOMARKER:

IDH1 mutation + Chr del(1p) + Chr del(19q) + BRAF V600E

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Entrez ID:

Related biomarkers:

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IDH1 mutation + Chr del(1p) + Chr del(19q) (10)

HER-2 amplification + RAS wild-type + BRAF wild-type (9)

BRAF V600K + LDH elevation (3)

BRAF V600E + MSI-H (2)

BRAF V600E + PD-L1 expression (2)

BRAF V600E + PD-L1 expression (2)

BRAF V600E + PIK3CA mutation + SMAD4 mutation + MSI-H/dMMR (2)

BRAF V600E + ROS1 fusion (2)

BRAF mutation + MET amplification (2)

BRAF mutation + MSI-L/dMMR (2)

BRAF mutation + TERT overexpression (2)

BRAF wild-type + HER-2 positive (2)

EZR overexpression + BRAF V600E (2)

IDH1 mutation + BRAF V600E (2)

IDH2 mutation + BRAF V600E (2)

IDH2 mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (2)

MSI-H/dMMR + BRAF V600E (2)

PD-L1 expression + NRAS Q61R + BRAF D594N (2)

PD-L1 overexpression + BRAF V600E (2)

RAS wild-type + BRAF wild-type + HER-2 positive (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK2 fusion (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK3 fusion (2)

IDH1 mutation + NTRK1 fusion (2)

IDH1 mutation + NTRK2 fusion (2)

IDH1 mutation + NTRK3 fusion (2)

MYC overexpression + IDH1 mutation (2)

ALK fusion + EGFR exon 19 deletion + BRAF G466V + MAP2K1 F129L (1)

ALK rearrangement + ALK I1171N + ALK V1180L + BRCA2 F2801fs (1)

BRAF E501Q + PD-L1 negative (1)

BRAF V600 + LDH elevation (1)

BRAF V600 + LDH elevation + PD-L1 negative (1)

BRAF V600E + CDKN2A deletion + MYCN amplification (1)

BRAF V600E + CDKN2A deletion + RB1 expression (1)

BRAF V600E + EGFR expression (1)

BRAF V600E + PTEN deletion (1)

BRAF V600E + SOX2 amplification (1)

BRAF V600K + CDKN2A deletion + RB1 expression (1)

BRAF mutation + PD-L1 overexpression (1)

BRAF mutation + TMB-H (1)

BRAF mutation + TMB-L + MSI-L/dMMR (1)

BRAF negative + GKAP1-NTRK2 exon 10-16 in-frame fusion (1)

BRAF wild-type + HGF elevation (1)

CD8 elevation + BRAF V600 (1)

Chr t(11;14) + BRAF mutation (1)

EGFR exon 19 deletion + BRAF G464A (1)

EGFR overexpression + BRAF V600E (1)

EGFR overexpression + BRAF mutation (1)

HER-2 amplification + BRAF wild-type (1)

HR positive + BRAF V600E (1)

KIAA1549-BRAF fusion + MET amplification (1)

KIAA1549-BRAF fusion + PTEN deletion (1)

KRAS wild-type + BRAF V600E (1)

LDH elevation + BRAF mutation (1)

MAP2K1 mutation + BRAF wild-type (1)

MSI-H/dMMR + BRAF Mutation (1)

MSI-H/dMMR + KRAS wild-type + BRAF wild-type (1)

NRAS mutation + BRAF wild-type (1)

PD-L1 expression + BRAF negative (1)

PIK3CA mutation + BRAF wild-type (1)

SEMA6A overexpression + BRAF mutation (1)

SRC overexpression + BRAF V600E (1)

TNFAIP3 overexpression + BRAF mutation (1)

IDH wild-type + FGFR3 S249C + TP53 V73fs (1)

IDH1 R132S + H3K27me3 loss + MET exon 14 skipping mutation (1)

IDH1 mutation + ATRX deletion + TP53 deletion (1)

IDH1 mutation + FGFR2 fusion (1)

IDH1 mutation + FGFR2 rearrangement (1)

IDH1 mutation + MGMT promoter methylation (1)

IDH1 mutation + MYC amplification + MAPRE1 overexpression (1)

IDH1 mutation + TMB-L (1)

IDH1 mutation + WT1 overexpression (1)

PD-L1 overexpression + BRAF mutation (0)

IDH1 mutation + Chr del(1p) + Chr del(19q) + MGMT promoter methylation (0)

IDH1 mutation + Chr del(1p) + Chr del(19q) (10)

HER-2 amplification + RAS wild-type + BRAF wild-type (9)

BRAF V600K + LDH elevation (3)

BRAF V600E + MSI-H (2)

BRAF V600E + PD-L1 expression (2)

BRAF V600E + PD-L1 expression (2)

BRAF V600E + PIK3CA mutation + SMAD4 mutation + MSI-H/dMMR (2)

BRAF V600E + ROS1 fusion (2)

BRAF mutation + MET amplification (2)

BRAF mutation + MSI-L/dMMR (2)

BRAF mutation + TERT overexpression (2)

BRAF wild-type + HER-2 positive (2)

EZR overexpression + BRAF V600E (2)

IDH1 mutation + BRAF V600E (2)

IDH2 mutation + BRAF V600E (2)

IDH2 mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (2)

MSI-H/dMMR + BRAF V600E (2)

PD-L1 expression + NRAS Q61R + BRAF D594N (2)

PD-L1 overexpression + BRAF V600E (2)

RAS wild-type + BRAF wild-type + HER-2 positive (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK2 fusion (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK3 fusion (2)

IDH1 mutation + NTRK1 fusion (2)

IDH1 mutation + NTRK2 fusion (2)

IDH1 mutation + NTRK3 fusion (2)

MYC overexpression + IDH1 mutation (2)

ALK fusion + EGFR exon 19 deletion + BRAF G466V + MAP2K1 F129L (1)

ALK rearrangement + ALK I1171N + ALK V1180L + BRCA2 F2801fs (1)

BRAF E501Q + PD-L1 negative (1)

BRAF V600 + LDH elevation (1)

BRAF V600 + LDH elevation + PD-L1 negative (1)

BRAF V600E + CDKN2A deletion + MYCN amplification (1)

BRAF V600E + CDKN2A deletion + RB1 expression (1)

BRAF V600E + EGFR expression (1)

BRAF V600E + PTEN deletion (1)

BRAF V600E + SOX2 amplification (1)

BRAF V600K + CDKN2A deletion + RB1 expression (1)

BRAF mutation + PD-L1 overexpression (1)

BRAF mutation + TMB-H (1)

BRAF mutation + TMB-L + MSI-L/dMMR (1)

BRAF negative + GKAP1-NTRK2 exon 10-16 in-frame fusion (1)

BRAF wild-type + HGF elevation (1)

CD8 elevation + BRAF V600 (1)

Chr t(11;14) + BRAF mutation (1)

EGFR exon 19 deletion + BRAF G464A (1)

EGFR overexpression + BRAF V600E (1)

EGFR overexpression + BRAF mutation (1)

HER-2 amplification + BRAF wild-type (1)

HR positive + BRAF V600E (1)

KIAA1549-BRAF fusion + MET amplification (1)

KIAA1549-BRAF fusion + PTEN deletion (1)

KRAS wild-type + BRAF V600E (1)

LDH elevation + BRAF mutation (1)

MAP2K1 mutation + BRAF wild-type (1)

MSI-H/dMMR + BRAF Mutation (1)

MSI-H/dMMR + KRAS wild-type + BRAF wild-type (1)

NRAS mutation + BRAF wild-type (1)

PD-L1 expression + BRAF negative (1)

PIK3CA mutation + BRAF wild-type (1)

SEMA6A overexpression + BRAF mutation (1)

SRC overexpression + BRAF V600E (1)

TNFAIP3 overexpression + BRAF mutation (1)

IDH wild-type + FGFR3 S249C + TP53 V73fs (1)

IDH1 R132S + H3K27me3 loss + MET exon 14 skipping mutation (1)

IDH1 mutation + ATRX deletion + TP53 deletion (1)

IDH1 mutation + FGFR2 fusion (1)

IDH1 mutation + FGFR2 rearrangement (1)

IDH1 mutation + MGMT promoter methylation (1)

IDH1 mutation + MYC amplification + MAPRE1 overexpression (1)

IDH1 mutation + TMB-L (1)

IDH1 mutation + WT1 overexpression (1)

PD-L1 overexpression + BRAF mutation (0)

IDH1 mutation + Chr del(1p) + Chr del(19q) + MGMT promoter methylation (0)

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IDH1 mutation + Chr del(1p) + Chr del(19q) + BRAF V600E	Oligodendroglioma	IDH1 mutation + Chr del(1p) + Chr del(19q) + BRAF V600E	Oligodendroglioma	vemurafenib + cobimetinib Sensitive: A2 - Guideline vemurafenib + cobimetinib Sensitive : A2	vemurafenib + cobimetinib Sensitive: A2 - Guideline vemurafenib + cobimetinib Sensitive : A2
IDH1 mutation + Chr del(1p) + Chr del(19q) + BRAF V600E	Oligodendroglioma	IDH1 mutation + Chr del(1p) + Chr del(19q) + BRAF V600E	Oligodendroglioma	trametinib + dabrafenib Sensitive: A2 - Guideline trametinib + dabrafenib Sensitive : A2	trametinib + dabrafenib Sensitive: A2 - Guideline trametinib + dabrafenib Sensitive : A2