HER-2 negative	HER2 Negative Breast Cancer	HER-2 negative	HER2 Negative Breast Cancer	APG-1387 Sensitive: C3 – Early Trials APG-1387 Sensitive : C3	APG-1387 Sensitive: C3 – Early Trials APG-1387 Sensitive : C3
BRCA1 mutation	Pancreatic Cancer	BRCA1 mutation	Pancreatic Cancer	olaparib + APG-1387 Sensitive: D – Preclinical olaparib + APG-1387 Sensitive : D	olaparib + APG-1387 Sensitive: D – Preclinical olaparib + APG-1387 Sensitive : D
BRCA2 mutation	Pancreatic Cancer	BRCA2 mutation	Pancreatic Cancer	olaparib + APG-1387 Sensitive: D – Preclinical olaparib + APG-1387 Sensitive : D	olaparib + APG-1387 Sensitive: D – Preclinical olaparib + APG-1387 Sensitive : D
KRAS mutation	Pancreatic Cancer	KRAS mutation	Pancreatic Cancer	olaparib + APG-1387 Sensitive: D – Preclinical olaparib + APG-1387 Sensitive : D	olaparib + APG-1387 Sensitive: D – Preclinical olaparib + APG-1387 Sensitive : D
FADD overexpression	Squamous Cell Carcinoma of Head and Neck	FADD overexpression	Squamous Cell Carcinoma of Head and Neck	IGM-9427 Sensitive: D – Preclinical IGM-9427 Sensitive : D	IGM-9427 Sensitive: D – Preclinical IGM-9427 Sensitive : D
FADD overexpression + BIRC2 overexpression	Squamous Cell Carcinoma of Head and Neck	FADD overexpression + BIRC2 overexpression	Squamous Cell Carcinoma of Head and Neck	IGM-9427 Sensitive: D – Preclinical IGM-9427 Sensitive : D	IGM-9427 Sensitive: D – Preclinical IGM-9427 Sensitive : D
FADD amplification	Squamous Cell Carcinoma of Head and Neck	FADD amplification	Squamous Cell Carcinoma of Head and Neck	IGM-9427 Sensitive: D – Preclinical IGM-9427 Sensitive : D	IGM-9427 Sensitive: D – Preclinical IGM-9427 Sensitive : D
FADD amplification + BIRC2 amplification	Squamous Cell Carcinoma of Head and Neck	FADD amplification + BIRC2 amplification	Squamous Cell Carcinoma of Head and Neck	IGM-9427 Sensitive: D – Preclinical IGM-9427 Sensitive : D	IGM-9427 Sensitive: D – Preclinical IGM-9427 Sensitive : D
BIRC2 overexpression + BIRC3 overexpression	Squamous Cell Carcinoma of Head and Neck	BIRC2 overexpression + BIRC3 overexpression	Squamous Cell Carcinoma of Head and Neck	AZD5582 Sensitive: D – Preclinical AZD5582 Sensitive : D	AZD5582 Sensitive: D – Preclinical AZD5582 Sensitive : D
RB1 deletion	Estrogen Receptor Positive Breast Cancer	RB1 deletion	Estrogen Receptor Positive Breast Cancer	IGM-9427 Sensitive: D – Preclinical IGM-9427 Sensitive : D	IGM-9427 Sensitive: D – Preclinical IGM-9427 Sensitive : D

IAP inhibitor

IAP inhibitor

Associations(10)

Associations
(10)