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BIOMARKER:
HER-2 A775_G776insYVMA
i
Other names:
ERBB2, CD340, HER-2, HER2, NEU, NGL, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
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Entrez ID:
2064
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
HER-2 amplification (129)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
HER-2 amplification + MET amplification (1)
HER-2 amplification + PTEN deletion (1)
HER-2 exon 19 deletion (1)
MYC amplification + HER-2 amplification (1)
HER-2 amplification + CDK12 amplification (0)
YES1 amplification + HER-2 amplification (0)
HER-2 amplification (129)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
HER-2 amplification + MET amplification (1)
HER-2 amplification + PTEN deletion (1)
HER-2 exon 19 deletion (1)
MYC amplification + HER-2 amplification (1)
HER-2 amplification + CDK12 amplification (0)
YES1 amplification + HER-2 amplification (0)
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Trials
VERI cancer hierarchy
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HER-2 A775_G776insYVMA
Non Small Cell Lung Cancer
HER-2 A775_G776insYVMA
Non Small Cell Lung Cancer
rivoceranib + pyrotinib
Sensitive: C3 – Early Trials
rivoceranib + pyrotinib
Sensitive
:
C3
rivoceranib + pyrotinib
Sensitive: C3 – Early Trials
rivoceranib + pyrotinib
Sensitive
:
C3
HER-2 A775_G776insYVMA
Non Small Cell Lung Cancer
HER-2 A775_G776insYVMA
Non Small Cell Lung Cancer
afatinib
Sensitive: C3 – Early Trials
afatinib
Sensitive
:
C3
afatinib
Sensitive: C3 – Early Trials
afatinib
Sensitive
:
C3
HER-2 A775_G776insYVMA
Non Small Cell Lung Cancer
HER-2 A775_G776insYVMA
Non Small Cell Lung Cancer
pyrotinib
Sensitive: C3 – Early Trials
pyrotinib
Sensitive
:
C3
pyrotinib
Sensitive: C3 – Early Trials
pyrotinib
Sensitive
:
C3
HER-2 A775_G776insYVMA
Non Small Cell Lung Cancer
HER-2 A775_G776insYVMA
Non Small Cell Lung Cancer
dacomitinib
Sensitive: C3 – Early Trials
dacomitinib
Sensitive
:
C3
dacomitinib
Sensitive: C3 – Early Trials
dacomitinib
Sensitive
:
C3
HER-2 A775_G776insYVMA
Non Small Cell Lung Cancer
HER-2 A775_G776insYVMA
Non Small Cell Lung Cancer
ado-trastuzumab emtansine
Sensitive: C3 – Early Trials
ado-trastuzumab emtansine
Sensitive
:
C3
ado-trastuzumab emtansine
Sensitive: C3 – Early Trials
ado-trastuzumab emtansine
Sensitive
:
C3
HER-2 A775_G776insYVMA
Lung Adenocarcinoma
HER-2 A775_G776insYVMA
Lung Adenocarcinoma
tarloxotinib bromide
Sensitive: C4 – Case Studies
tarloxotinib bromide
Sensitive
:
C4
tarloxotinib bromide
Sensitive: C4 – Case Studies
tarloxotinib bromide
Sensitive
:
C4
HER-2 A775_G776insYVMA
Lung Adenocarcinoma
HER-2 A775_G776insYVMA
Lung Adenocarcinoma
ado-trastuzumab emtansine
Sensitive: C4 – Case Studies
ado-trastuzumab emtansine
Sensitive
:
C4
ado-trastuzumab emtansine
Sensitive: C4 – Case Studies
ado-trastuzumab emtansine
Sensitive
:
C4
HER-2 A775_G776insYVMA
Lung Adenocarcinoma
HER-2 A775_G776insYVMA
Lung Adenocarcinoma
afatinib
Sensitive: C4 – Case Studies
afatinib
Sensitive
:
C4
afatinib
Sensitive: C4 – Case Studies
afatinib
Sensitive
:
C4
HER-2 A775_G776insYVMA
Lung Adenocarcinoma
HER-2 A775_G776insYVMA
Lung Adenocarcinoma
pyrotinib
Sensitive: D – Preclinical
pyrotinib
Sensitive
:
D
pyrotinib
Sensitive: D – Preclinical
pyrotinib
Sensitive
:
D
HER-2 A775_G776insYVMA
Non Small Cell Lung Cancer
HER-2 A775_G776insYVMA
Non Small Cell Lung Cancer
mobocertinib
Sensitive: D – Preclinical
mobocertinib
Sensitive
:
D
mobocertinib
Sensitive: D – Preclinical
mobocertinib
Sensitive
:
D
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