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DRUG CLASS:
HDAC inhibitor
DRUG CLASS:
HDAC inhibitor
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News alerts, weekly reports and conference planners
Related drugs:
‹
chidamide (23)
vorinostat (19)
panobinostat (15)
romidepsin (9)
entinostat (9)
CUDC-907 (8)
OKI-179 (4)
SB939 (4)
belinostat (2)
CG-781 (2)
MGCD0103 (2)
REC-2282 (1)
4SC-202 (1)
JNJ 26481585 (1)
CUDC-101 (0)
givinostat (0)
resminostat (0)
RG2833 (0)
sulforafan alfadex (0)
CKD-581 (0)
histone deacetylase inhibitors/hypomethylating agents (0)
CG-745 (0)
kt-3000 series (0)
kt-3283 (0)
VRx-3996 (0)
MTX110 (0)
SHP-141 (0)
OBP-801 (0)
EDO-S101 (0)
VTR-297 (0)
CXD101 (0)
chidamide (23)
vorinostat (19)
panobinostat (15)
romidepsin (9)
entinostat (9)
CUDC-907 (8)
OKI-179 (4)
SB939 (4)
belinostat (2)
CG-781 (2)
MGCD0103 (2)
REC-2282 (1)
4SC-202 (1)
JNJ 26481585 (1)
CUDC-101 (0)
givinostat (0)
resminostat (0)
RG2833 (0)
sulforafan alfadex (0)
CKD-581 (0)
histone deacetylase inhibitors/hypomethylating agents (0)
CG-745 (0)
kt-3000 series (0)
kt-3283 (0)
VRx-3996 (0)
MTX110 (0)
SHP-141 (0)
OBP-801 (0)
EDO-S101 (0)
VTR-297 (0)
CXD101 (0)
›
Associations
(106)
News
Trials
VERI cancer hierarchy
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No biomarker
Multiple Myeloma
No biomarker
Multiple Myeloma
bortezomib + panobinostat
Sensitive: A1 - Approval
bortezomib + panobinostat
Sensitive
:
A1
bortezomib + panobinostat
Sensitive: A1 - Approval
bortezomib + panobinostat
Sensitive
:
A1
No biomarker
Peripheral T-cell Lymphoma
No biomarker
Peripheral T-cell Lymphoma
belinostat
Sensitive: A1 - Approval
belinostat
Sensitive
:
A1
belinostat
Sensitive: A1 - Approval
belinostat
Sensitive
:
A1
BCL2 expression + MYC expression
Diffuse Large B Cell Lymphoma
BCL2 expression + MYC expression
Diffuse Large B Cell Lymphoma
chidamide
Sensitive: A1 - Approval
chidamide
Sensitive
:
A1
chidamide
Sensitive: A1 - Approval
chidamide
Sensitive
:
A1
No biomarker
Cutaneous T-cell Lymphoma
No biomarker
Cutaneous T-cell Lymphoma
vorinostat
Sensitive: A1 - Approval
vorinostat
Sensitive
:
A1
vorinostat
Sensitive: A1 - Approval
vorinostat
Sensitive
:
A1
No biomarker
Multiple Myeloma
No biomarker
Multiple Myeloma
panobinostat
Sensitive: A2 - Guideline
panobinostat
Sensitive
:
A2
panobinostat
Sensitive: A2 - Guideline
panobinostat
Sensitive
:
A2
No biomarker
Peripheral T-cell Lymphoma
No biomarker
Peripheral T-cell Lymphoma
romidepsin
Sensitive: A2 - Guideline
romidepsin
Sensitive
:
A2
romidepsin
Sensitive: A2 - Guideline
romidepsin
Sensitive
:
A2
No biomarker
Follicular Lymphoma
No biomarker
Follicular Lymphoma
CG-781
Sensitive: B - Late Trials
CG-781
Sensitive
:
B
CG-781
Sensitive: B - Late Trials
CG-781
Sensitive
:
B
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
entinostat
Resistant: B - Late Trials
entinostat
Resistant
:
B
entinostat
Resistant: B - Late Trials
entinostat
Resistant
:
B
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
chidamide
Sensitive: B - Late Trials
chidamide
Sensitive
:
B
chidamide
Sensitive: B - Late Trials
chidamide
Sensitive
:
B
GNAQ mutation
Melanoma
GNAQ mutation
Melanoma
vorinostat
Sensitive: C2 – Inclusion Criteria
vorinostat
Sensitive
:
C2
vorinostat
Sensitive: C2 – Inclusion Criteria
vorinostat
Sensitive
:
C2
GNA11 mutation
Melanoma
GNA11 mutation
Melanoma
vorinostat
Sensitive: C2 – Inclusion Criteria
vorinostat
Sensitive
:
C2
vorinostat
Sensitive: C2 – Inclusion Criteria
vorinostat
Sensitive
:
C2
BAP1 mutation
Melanoma
BAP1 mutation
Melanoma
vorinostat
Sensitive: C2 – Inclusion Criteria
vorinostat
Sensitive
:
C2
vorinostat
Sensitive: C2 – Inclusion Criteria
vorinostat
Sensitive
:
C2
HR positive
Breast Cancer
HR positive
Breast Cancer
entinostat
Sensitive: C2 – Inclusion Criteria
entinostat
Sensitive
:
C2
entinostat
Sensitive: C2 – Inclusion Criteria
entinostat
Sensitive
:
C2
ER positive
Estrogen Receptor Positive Breast Cancer
ER positive
Estrogen Receptor Positive Breast Cancer
entinostat
Sensitive: C2 – Inclusion Criteria
entinostat
Sensitive
:
C2
entinostat
Sensitive: C2 – Inclusion Criteria
entinostat
Sensitive
:
C2
HR positive
Hormone Receptor Positive Breast Cancer
HR positive
Hormone Receptor Positive Breast Cancer
HDAC inhibitor + exemestane
Sensitive: C2 – Inclusion Criteria
HDAC inhibitor + exemestane
Sensitive
:
C2
HDAC inhibitor + exemestane
Sensitive: C2 – Inclusion Criteria
HDAC inhibitor + exemestane
Sensitive
:
C2
ALK positive
Peripheral T-cell Lymphoma
ALK positive
Peripheral T-cell Lymphoma
chidamide
Sensitive: C2 – Inclusion Criteria
chidamide
Sensitive
:
C2
chidamide
Sensitive: C2 – Inclusion Criteria
chidamide
Sensitive
:
C2
HDAC2 expression
Renal Cell Carcinoma
HDAC2 expression
Renal Cell Carcinoma
pazopanib + CG-781
Sensitive: C3 – Early Trials
pazopanib + CG-781
Sensitive
:
C3
pazopanib + CG-781
Sensitive: C3 – Early Trials
pazopanib + CG-781
Sensitive
:
C3
H3.3K27M
Glioma
H3.3K27M
Glioma
panobinostat
Sensitive: C3 – Early Trials
panobinostat
Sensitive
:
C3
panobinostat
Sensitive: C3 – Early Trials
panobinostat
Sensitive
:
C3
KMT2D mutation
Diffuse Large B Cell Lymphoma
KMT2D mutation
Diffuse Large B Cell Lymphoma
chidamide
Resistant: C3 – Early Trials
chidamide
Resistant
:
C3
chidamide
Resistant: C3 – Early Trials
chidamide
Resistant
:
C3
FLT3-ITD mutation + SKI overexpression
Acute Myelogenous Leukemia
FLT3-ITD mutation + SKI overexpression
Acute Myelogenous Leukemia
HDAC inhibitor
Sensitive: C3 – Early Trials
HDAC inhibitor
Sensitive
:
C3
HDAC inhibitor
Sensitive: C3 – Early Trials
HDAC inhibitor
Sensitive
:
C3
S100A9 expression
Multiple Myeloma
S100A9 expression
Multiple Myeloma
bortezomib + panobinostat
Resistant: C3 – Early Trials
bortezomib + panobinostat
Resistant
:
C3
bortezomib + panobinostat
Resistant: C3 – Early Trials
bortezomib + panobinostat
Resistant
:
C3
S100A8 expression
Multiple Myeloma
S100A8 expression
Multiple Myeloma
bortezomib + panobinostat
Resistant: C3 – Early Trials
bortezomib + panobinostat
Resistant
:
C3
bortezomib + panobinostat
Resistant: C3 – Early Trials
bortezomib + panobinostat
Resistant
:
C3
KMT2A-PTD
Acute Myelogenous Leukemia
KMT2A-PTD
Acute Myelogenous Leukemia
cytarabine + decitabine + vorinostat
Sensitive: C3 – Early Trials
cytarabine + decitabine + vorinostat
Sensitive
:
C3
cytarabine + decitabine + vorinostat
Sensitive: C3 – Early Trials
cytarabine + decitabine + vorinostat
Sensitive
:
C3
HDAC1 amplification
Soft Tissue Sarcoma
HDAC1 amplification
Soft Tissue Sarcoma
PD1 inhibitor + chidamide
Sensitive: C3 – Early Trials
PD1 inhibitor + chidamide
Sensitive
:
C3
PD1 inhibitor + chidamide
Sensitive: C3 – Early Trials
PD1 inhibitor + chidamide
Sensitive
:
C3
TNFRSF8 negative
Peripheral T-cell Lymphoma
TNFRSF8 negative
Peripheral T-cell Lymphoma
chidamide
Sensitive: C3 – Early Trials
chidamide
Sensitive
:
C3
chidamide
Sensitive: C3 – Early Trials
chidamide
Sensitive
:
C3
PD-L1 expression
Non-Hodgkin’s Lymphoma
PD-L1 expression
Non-Hodgkin’s Lymphoma
sintilimab + chidamide
Sensitive: C3 – Early Trials
sintilimab + chidamide
Sensitive
:
C3
sintilimab + chidamide
Sensitive: C3 – Early Trials
sintilimab + chidamide
Sensitive
:
C3
MYC mutation
Diffuse Large B Cell Lymphoma
MYC mutation
Diffuse Large B Cell Lymphoma
CUDC-907
Sensitive: C3 – Early Trials
CUDC-907
Sensitive
:
C3
CUDC-907
Sensitive: C3 – Early Trials
CUDC-907
Sensitive
:
C3
IFNG gene signature overexpression
Melanoma
IFNG gene signature overexpression
Melanoma
nivolumab + 4SC-202
Sensitive: C3 – Early Trials
nivolumab + 4SC-202
Sensitive
:
C3
nivolumab + 4SC-202
Sensitive: C3 – Early Trials
nivolumab + 4SC-202
Sensitive
:
C3
LDH-L
Uveal Melanoma
LDH-L
Uveal Melanoma
pembrolizumab + entinostat
Sensitive: C3 – Early Trials
pembrolizumab + entinostat
Sensitive
:
C3
pembrolizumab + entinostat
Sensitive: C3 – Early Trials
pembrolizumab + entinostat
Sensitive
:
C3
ERBB3 overexpression
Triple Negative Breast Cancer
ERBB3 overexpression
Triple Negative Breast Cancer
HDAC inhibitor + AKT2 inhibitor
Sensitive: C3 – Early Trials
HDAC inhibitor + AKT2 inhibitor
Sensitive
:
C3
HDAC inhibitor + AKT2 inhibitor
Sensitive: C3 – Early Trials
HDAC inhibitor + AKT2 inhibitor
Sensitive
:
C3
ERBB3 overexpression
Triple Negative Breast Cancer
ERBB3 overexpression
Triple Negative Breast Cancer
HDAC inhibitor + AKT1 inhibitor
Sensitive: C3 – Early Trials
HDAC inhibitor + AKT1 inhibitor
Sensitive
:
C3
HDAC inhibitor + AKT1 inhibitor
Sensitive: C3 – Early Trials
HDAC inhibitor + AKT1 inhibitor
Sensitive
:
C3
ERBB3 overexpression
Triple Negative Breast Cancer
ERBB3 overexpression
Triple Negative Breast Cancer
romidepsin
Sensitive: C3 – Early Trials
romidepsin
Sensitive
:
C3
romidepsin
Sensitive: C3 – Early Trials
romidepsin
Sensitive
:
C3
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