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BIOMARKER:
FLT3-TKD mutation
i
Other names:
FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
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Entrez ID:
2322
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
FLT3 amplification (1)
FLT3 amplification (1)
›
Related tests:
LeukoStrat® CDx FLT3 Mutation Assay (6)
LeukoStrat® CDx FLT3 Mutation Assay (6)
Associations
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Trials
VERI cancer hierarchy
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FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
midostaurin
Sensitive: A2 - Guideline
midostaurin
Sensitive
:
A2
midostaurin
Sensitive: A2 - Guideline
midostaurin
Sensitive
:
A2
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
gilteritinib
Sensitive: A2 - Guideline
gilteritinib
Sensitive
:
A2
gilteritinib
Sensitive: A2 - Guideline
gilteritinib
Sensitive
:
A2
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
cytarabine + midostaurin + daunorubicin
Sensitive: A2 - Guideline
cytarabine + midostaurin + daunorubicin
Sensitive
:
A2
cytarabine + midostaurin + daunorubicin
Sensitive: A2 - Guideline
cytarabine + midostaurin + daunorubicin
Sensitive
:
A2
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
venetoclax
Sensitive: B - Late Trials
venetoclax
Sensitive
:
B
venetoclax
Sensitive: B - Late Trials
venetoclax
Sensitive
:
B
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
LY3009120
Sensitive: C3 – Early Trials
LY3009120
Sensitive
:
C3
LY3009120
Sensitive: C3 – Early Trials
LY3009120
Sensitive
:
C3
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
venetoclax + gilteritinib
Sensitive: C3 – Early Trials
venetoclax + gilteritinib
Sensitive
:
C3
venetoclax + gilteritinib
Sensitive: C3 – Early Trials
venetoclax + gilteritinib
Sensitive
:
C3
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
sorafenib + gilteritinib
Sensitive: C3 – Early Trials
sorafenib + gilteritinib
Sensitive
:
C3
sorafenib + gilteritinib
Sensitive: C3 – Early Trials
sorafenib + gilteritinib
Sensitive
:
C3
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
ARO-002
Sensitive: C3 – Early Trials
ARO-002
Sensitive
:
C3
ARO-002
Sensitive: C3 – Early Trials
ARO-002
Sensitive
:
C3
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3 inhibitor
Sensitive: C3 – Early Trials
FLT3 inhibitor
Sensitive
:
C3
FLT3 inhibitor
Sensitive: C3 – Early Trials
FLT3 inhibitor
Sensitive
:
C3
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
midostaurin + gemtuzumab ozogamicin
Sensitive: C3 – Early Trials
midostaurin + gemtuzumab ozogamicin
Sensitive
:
C3
midostaurin + gemtuzumab ozogamicin
Sensitive: C3 – Early Trials
midostaurin + gemtuzumab ozogamicin
Sensitive
:
C3
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
HEC73543
Sensitive: C3 – Early Trials
HEC73543
Sensitive
:
C3
HEC73543
Sensitive: C3 – Early Trials
HEC73543
Sensitive
:
C3
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
JRF104
Sensitive: D – Preclinical
JRF104
Sensitive
:
D
JRF104
Sensitive: D – Preclinical
JRF104
Sensitive
:
D
FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-TKD mutation
Acute Myelogenous Leukemia
PHI-101
Sensitive: D – Preclinical
PHI-101
Sensitive
:
D
PHI-101
Sensitive: D – Preclinical
PHI-101
Sensitive
:
D
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