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BIOMARKER:
FGFR2 overexpression
i
Other names:
FGFR2, BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, Fibroblast growth factor receptor
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Entrez ID:
2263
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
BAP1 mutation + FGFR2 fusion (1)
FGFR2 underexpression + FGFR3 mutation (1)
IDH1 mutation + FGFR2 fusion (1)
IDH1 mutation + FGFR2 rearrangement (1)
NOTCH1 positive + FGFR2 mutation (1)
PBRM1 mutation + FGFR2 fusion (1)
TP53 mutation + FGFR2 fusion (1)
FGFR2 K660N + TP53 deletion (0)
BAP1 mutation + FGFR2 fusion (1)
FGFR2 underexpression + FGFR3 mutation (1)
IDH1 mutation + FGFR2 fusion (1)
IDH1 mutation + FGFR2 rearrangement (1)
NOTCH1 positive + FGFR2 mutation (1)
PBRM1 mutation + FGFR2 fusion (1)
TP53 mutation + FGFR2 fusion (1)
FGFR2 K660N + TP53 deletion (0)
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Associations
News
Trials
VERI cancer hierarchy
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FGFR2 overexpression
Gastric Cancer
FGFR2 overexpression
Gastric Cancer
AMG 552
Sensitive: C2 – Inclusion Criteria
AMG 552
Sensitive
:
C2
AMG 552
Sensitive: C2 – Inclusion Criteria
AMG 552
Sensitive
:
C2
FGFR2 overexpression
Lung Non-Small Cell Squamous Cancer
FGFR2 overexpression
Lung Non-Small Cell Squamous Cancer
BAY 1163877
Resistant: C3 – Early Trials
BAY 1163877
Resistant
:
C3
BAY 1163877
Resistant: C3 – Early Trials
BAY 1163877
Resistant
:
C3
FGFR2 overexpression
Breast Cancer
FGFR2 overexpression
Breast Cancer
futibatinib
Sensitive: C3 – Early Trials
futibatinib
Sensitive
:
C3
futibatinib
Sensitive: C3 – Early Trials
futibatinib
Sensitive
:
C3
FGFR2 overexpression
Hormone Receptor Positive Breast Cancer
FGFR2 overexpression
Hormone Receptor Positive Breast Cancer
palbociclib + BAY 1163877
Sensitive: C3 – Early Trials
palbociclib + BAY 1163877
Sensitive
:
C3
palbociclib + BAY 1163877
Sensitive: C3 – Early Trials
palbociclib + BAY 1163877
Sensitive
:
C3
FGFR2 overexpression
Gastrointestinal Cancer
FGFR2 overexpression
Gastrointestinal Cancer
ARQ 087
Sensitive: D – Preclinical
ARQ 087
Sensitive
:
D
ARQ 087
Sensitive: D – Preclinical
ARQ 087
Sensitive
:
D
FGFR2 overexpression
Breast Cancer
FGFR2 overexpression
Breast Cancer
ponatinib
Sensitive: D – Preclinical
ponatinib
Sensitive
:
D
ponatinib
Sensitive: D – Preclinical
ponatinib
Sensitive
:
D
FGFR2 overexpression
Breast Cancer
FGFR2 overexpression
Breast Cancer
FGFR inhibitor
Sensitive: D – Preclinical
FGFR inhibitor
Sensitive
:
D
FGFR inhibitor
Sensitive: D – Preclinical
FGFR inhibitor
Sensitive
:
D
FGFR2 overexpression
Cholangiocarcinoma
FGFR2 overexpression
Cholangiocarcinoma
NXP800
Sensitive: D – Preclinical
NXP800
Sensitive
:
D
NXP800
Sensitive: D – Preclinical
NXP800
Sensitive
:
D
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