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BIOMARKER:
FGFR2 overexpression
i
Other names:
FGFR2, BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, Fibroblast growth factor receptor
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Entrez ID:
2263
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
FGFR2 mutation (30)
FGFR2 N549K (7)
FGFR2 rearrangement (7)
FGFR2 P253R (3)
FGFR2 K310R (2)
FGFR2 translocation (2)
ARID1A K1238fs + FGFR2 R210Q (1)
BAP1 mutation + FGFR2 rearrangement (1)
FDFT1 rearrangement + FGFR2 rearrangement (1)
FGFR2 A391E (1)
FGFR2 B252W (1)
FGFR2 C382R (1)
FGFR2 E250G (1)
FGFR2 E565A (1)
FGFR2 E565G (1)
FGFR2 E565K (1)
FGFR2 F276C (1)
FGFR2 M540_I541insMM (1)
FGFR2 N549D (1)
FGFR2 N549H (1)
FGFR2 N549T (1)
FGFR2 N550K (1)
FGFR2 S252W (1)
FGFR2 V564F (1)
FGFR2 V564I (1)
FGFR2 V564L (1)
FGFR2 Y375C (1)
FGFR2 Y376C (1)
PIK3CA mutation + FGFR2 rearrangement (1)
PIK3CB mutation + FGFR2 rearrangement (1)
PIK3R1 mutation + FGFR2 rearrangement (1)
TP53 mutation + FGFR2 rearrangement (1)
FGFR2 C383R (0)
FGFR2 K660N (0)
FGFR2 W290C (0)
FGFR2 wild-type (0)
FGFR2 mutation (30)
FGFR2 N549K (7)
FGFR2 rearrangement (7)
FGFR2 P253R (3)
FGFR2 K310R (2)
FGFR2 translocation (2)
ARID1A K1238fs + FGFR2 R210Q (1)
BAP1 mutation + FGFR2 rearrangement (1)
FDFT1 rearrangement + FGFR2 rearrangement (1)
FGFR2 A391E (1)
FGFR2 B252W (1)
FGFR2 C382R (1)
FGFR2 E250G (1)
FGFR2 E565A (1)
FGFR2 E565G (1)
FGFR2 E565K (1)
FGFR2 F276C (1)
FGFR2 M540_I541insMM (1)
FGFR2 N549D (1)
FGFR2 N549H (1)
FGFR2 N549T (1)
FGFR2 N550K (1)
FGFR2 S252W (1)
FGFR2 V564F (1)
FGFR2 V564I (1)
FGFR2 V564L (1)
FGFR2 Y375C (1)
FGFR2 Y376C (1)
PIK3CA mutation + FGFR2 rearrangement (1)
PIK3CB mutation + FGFR2 rearrangement (1)
PIK3R1 mutation + FGFR2 rearrangement (1)
TP53 mutation + FGFR2 rearrangement (1)
FGFR2 C383R (0)
FGFR2 K660N (0)
FGFR2 W290C (0)
FGFR2 wild-type (0)
›
Associations
News
Trials
VERI cancer hierarchy
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FGFR2 overexpression
Gastric Cancer
FGFR2 overexpression
Gastric Cancer
AMG 552
Sensitive: C2 – Inclusion Criteria
AMG 552
Sensitive
:
C2
AMG 552
Sensitive: C2 – Inclusion Criteria
AMG 552
Sensitive
:
C2
FGFR2 overexpression
Lung Non-Small Cell Squamous Cancer
FGFR2 overexpression
Lung Non-Small Cell Squamous Cancer
BAY 1163877
Resistant: C3 – Early Trials
BAY 1163877
Resistant
:
C3
BAY 1163877
Resistant: C3 – Early Trials
BAY 1163877
Resistant
:
C3
FGFR2 overexpression
Breast Cancer
FGFR2 overexpression
Breast Cancer
futibatinib
Sensitive: C3 – Early Trials
futibatinib
Sensitive
:
C3
futibatinib
Sensitive: C3 – Early Trials
futibatinib
Sensitive
:
C3
FGFR2 overexpression
Hormone Receptor Positive Breast Cancer
FGFR2 overexpression
Hormone Receptor Positive Breast Cancer
palbociclib + BAY 1163877
Sensitive: C3 – Early Trials
palbociclib + BAY 1163877
Sensitive
:
C3
palbociclib + BAY 1163877
Sensitive: C3 – Early Trials
palbociclib + BAY 1163877
Sensitive
:
C3
FGFR2 overexpression
Gastrointestinal Cancer
FGFR2 overexpression
Gastrointestinal Cancer
ARQ 087
Sensitive: D – Preclinical
ARQ 087
Sensitive
:
D
ARQ 087
Sensitive: D – Preclinical
ARQ 087
Sensitive
:
D
FGFR2 overexpression
Breast Cancer
FGFR2 overexpression
Breast Cancer
ponatinib
Sensitive: D – Preclinical
ponatinib
Sensitive
:
D
ponatinib
Sensitive: D – Preclinical
ponatinib
Sensitive
:
D
FGFR2 overexpression
Breast Cancer
FGFR2 overexpression
Breast Cancer
FGFR inhibitor
Sensitive: D – Preclinical
FGFR inhibitor
Sensitive
:
D
FGFR inhibitor
Sensitive: D – Preclinical
FGFR inhibitor
Sensitive
:
D
FGFR2 overexpression
Cholangiocarcinoma
FGFR2 overexpression
Cholangiocarcinoma
NXP800
Sensitive: D – Preclinical
NXP800
Sensitive
:
D
NXP800
Sensitive: D – Preclinical
NXP800
Sensitive
:
D
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