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BIOMARKER:
FGFR1 overexpression + HR positive
i
Other names:
ESR1, Era, ESR, NR3A1, ER, ER beta, PGR, Progesterone receptor, Nuclear receptor subfamily 3 group C member 3, NR3C3, FGFR1, BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM, Fibroblast growth factor receptor 1
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Entrez ID:
2099
;
5241
;
2260
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
ER positive (199)
HR positive (184)
HR negative (25)
FGFR1 overexpression (20)
ER negative (13)
ER positive + PGR positive (12)
PGR positive (10)
HR positive + HER-2 negative (5)
FGFR1 expression (5)
ER expression (3)
ER overexpression (3)
IRF8 overexpression + ER negative (3)
ER positive + HER-2 negative (2)
ER positive + PGR negative (2)
HR negative + PD-L1 expression (2)
HR positive + ER overexpression (2)
HR positive + HER-2 underexpression (2)
PGR expression (2)
PGR overexpression (2)
AR positive + ER positive (1)
CETN2 overexpression + HR positive (1)
CETN2 overexpression + MLH3 overexpression + PCNA overexpression + HR positive (1)
CTSD positive + ER positive (1)
ER negative + HER-2 negative (1)
ER positive + CDK6 overexpression (1)
ER positive + PGR negative + HER-2 negative (1)
ER underexpression (1)
HDC overexpression + HR positive (1)
HER-2 underexpression + ER underexpression (1)
HR overexpression (1)
HR positive + AR positive (1)
HR positive + BRCA positive (1)
HR positive + CCNE1 overexpression (1)
HR positive + ERBB3 overexpression (1)
HR positive + ERBB3 underexpression (1)
HR positive + HER-2 positive (1)
HR positive + PD-L1 expression (1)
HR positive + PLK1 overexpression (1)
HR positive + TNFRSF11A overexpression (1)
MLH3 overexpression + HR positive (1)
NOTCH3 expression + ER positive + PGR positive (1)
PCNA overexpression + HR positive (1)
PD-L1 overexpression + ER positive (1)
RAD51 overexpression + HR positive (1)
RFC3 overexpression + ER positive (1)
TFF1 overexpression + ER positive (1)
TFF3 overexpression + ER positive (1)
TNFRSF1A overexpression + HR positive (1)
TYMS overexpression + HR positive (1)
PGR negative (1)
BIN3 expression + ER positive (0)
CCNA2 expression + ER positive (0)
CCNB2 expression + ER positive (0)
CTDSP1 expression + ER positive (0)
EPRS1 expression + ER positive (0)
ER negative + HER-2 positive (0)
ER negative + PGR positive (0)
ER positive + HER-2 positive (0)
ER positive + PGR positive + HER-2 positive (0)
FOXD1 expression + ER positive (0)
FTO expression + ER positive (0)
HER-2 negative + AR positive + ER positive (0)
HER-2 negative + ER positive (0)
HR negative + HER-2 positive (0)
MIEN1 expression + ER negative + PR negative (0)
NCOR2 overexpression + ER positive (0)
RBPMS expression + ER positive (0)
SLBP expression + ER positive (0)
WSB2 expression + ER positive (0)
HER-2 negative + PGR positive (0)
PGR positive + HER-2 positive (0)
ER positive (199)
HR positive (184)
HR negative (25)
FGFR1 overexpression (20)
ER negative (13)
ER positive + PGR positive (12)
PGR positive (10)
HR positive + HER-2 negative (5)
FGFR1 expression (5)
ER expression (3)
ER overexpression (3)
IRF8 overexpression + ER negative (3)
ER positive + HER-2 negative (2)
ER positive + PGR negative (2)
HR negative + PD-L1 expression (2)
HR positive + ER overexpression (2)
HR positive + HER-2 underexpression (2)
PGR expression (2)
PGR overexpression (2)
AR positive + ER positive (1)
CETN2 overexpression + HR positive (1)
CETN2 overexpression + MLH3 overexpression + PCNA overexpression + HR positive (1)
CTSD positive + ER positive (1)
ER negative + HER-2 negative (1)
ER positive + CDK6 overexpression (1)
ER positive + PGR negative + HER-2 negative (1)
ER underexpression (1)
HDC overexpression + HR positive (1)
HER-2 underexpression + ER underexpression (1)
HR overexpression (1)
HR positive + AR positive (1)
HR positive + BRCA positive (1)
HR positive + CCNE1 overexpression (1)
HR positive + ERBB3 overexpression (1)
HR positive + ERBB3 underexpression (1)
HR positive + HER-2 positive (1)
HR positive + PD-L1 expression (1)
HR positive + PLK1 overexpression (1)
HR positive + TNFRSF11A overexpression (1)
MLH3 overexpression + HR positive (1)
NOTCH3 expression + ER positive + PGR positive (1)
PCNA overexpression + HR positive (1)
PD-L1 overexpression + ER positive (1)
RAD51 overexpression + HR positive (1)
RFC3 overexpression + ER positive (1)
TFF1 overexpression + ER positive (1)
TFF3 overexpression + ER positive (1)
TNFRSF1A overexpression + HR positive (1)
TYMS overexpression + HR positive (1)
PGR negative (1)
BIN3 expression + ER positive (0)
CCNA2 expression + ER positive (0)
CCNB2 expression + ER positive (0)
CTDSP1 expression + ER positive (0)
EPRS1 expression + ER positive (0)
ER negative + HER-2 positive (0)
ER negative + PGR positive (0)
ER positive + HER-2 positive (0)
ER positive + PGR positive + HER-2 positive (0)
FOXD1 expression + ER positive (0)
FTO expression + ER positive (0)
HER-2 negative + AR positive + ER positive (0)
HER-2 negative + ER positive (0)
HR negative + HER-2 positive (0)
MIEN1 expression + ER negative + PR negative (0)
NCOR2 overexpression + ER positive (0)
RBPMS expression + ER positive (0)
SLBP expression + ER positive (0)
WSB2 expression + ER positive (0)
HER-2 negative + PGR positive (0)
PGR positive + HER-2 positive (0)
›
Associations
News
Trials
VERI cancer hierarchy
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FGFR1 overexpression + HR positive
HER2 Negative Breast Cancer
FGFR1 overexpression + HR positive
HER2 Negative Breast Cancer
ribociclib
Sensitive: C3 – Early Trials
ribociclib
Sensitive
:
C3
ribociclib
Sensitive: C3 – Early Trials
ribociclib
Sensitive
:
C3
FGFR1 overexpression + HR positive
HER2 Negative Breast Cancer
FGFR1 overexpression + HR positive
HER2 Negative Breast Cancer
E 3810
Sensitive: C3 – Early Trials
E 3810
Sensitive
:
C3
E 3810
Sensitive: C3 – Early Trials
E 3810
Sensitive
:
C3
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