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BIOMARKER:
EZH2 overexpression
i
Other names:
EZH2, ENX-1, EZH1, KMT6, KMT6A, Enhancer of zeste 2 polycomb repressive complex 2 subunit
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Entrez ID:
2146
Related biomarkers:
Expression
Mutation
CNA
Others
‹
EZH2 mutation (13)
EZH2 Y641F (5)
EZH2 W113C (2)
EZH2 Y641 (2)
BRAF V600E + TERT E441del + RET N579K + EZH2 D154E + CDK4 S259L (1)
EZH2 A490T (1)
EZH2 A682G (1)
EZH2 Y646 (1)
EZH2 Y646F (1)
EZH2 mutation + BCL2 translocation (1)
EZH2 rs201135441C>T (1)
EZH2 rs2302427C>G (1)
EZH2 wild-type (0)
EZH2 mutation (13)
EZH2 Y641F (5)
EZH2 W113C (2)
EZH2 Y641 (2)
BRAF V600E + TERT E441del + RET N579K + EZH2 D154E + CDK4 S259L (1)
EZH2 A490T (1)
EZH2 A682G (1)
EZH2 Y646 (1)
EZH2 Y646F (1)
EZH2 mutation + BCL2 translocation (1)
EZH2 rs201135441C>T (1)
EZH2 rs2302427C>G (1)
EZH2 wild-type (0)
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Trials
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EZH2 overexpression
Mediastinal B Cell Lymphoma
EZH2 overexpression
Mediastinal B Cell Lymphoma
lisocabtagene maraleucel
Resistant: C3 – Early Trials
lisocabtagene maraleucel
Resistant
:
C3
lisocabtagene maraleucel
Resistant: C3 – Early Trials
lisocabtagene maraleucel
Resistant
:
C3
EZH2 overexpression
Adrenal Cortex Carcinoma
EZH2 overexpression
Adrenal Cortex Carcinoma
EZH2 inhibitor
Sensitive: D – Preclinical
EZH2 inhibitor
Sensitive
:
D
EZH2 inhibitor
Sensitive: D – Preclinical
EZH2 inhibitor
Sensitive
:
D
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