^
BIOMARKER:

EZH2 mutation

i
Other names: EZH2, ENX-1, EZH1, KMT6, KMT6A, Enhancer of zeste 2 polycomb repressive complex 2 subunit
Entrez ID:
Related biomarkers:
EZH2 mutation
Follicular Lymphoma
tazemetostat
Sensitive: A1 - Approval
EZH2 mutation
AML
azacitidine
Sensitive: B - Late Trials
EZH2 mutation
Diffuse Large B Cell Lymphoma
tazemetostat
Sensitive: C1 - Off-label
EZH2 mutation
Follicular Lymphoma
rituximab
Resistant: C3 – Early Trials
EZH2 mutation
MDS
venetoclax
Sensitive: C3 – Early Trials
EZH2 mutation
Diffuse Large B Cell Lymphoma
CPI-169
Sensitive: D – Preclinical
EZH2 mutation
Diffuse Large B Cell Lymphoma
CPI-169 + CPI-203
Sensitive: D – Preclinical
EZH2 mutation
Follicular Lymphoma
CPI-169
Sensitive: D – Preclinical
EZH2 mutation
Lymphoma
EED inhibitor
Sensitive: D – Preclinical
EZH2 mutation
Diffuse Large B Cell Lymphoma
SHR2554
Sensitive: D – Preclinical
EZH2 mutation
Diffuse Large B Cell Lymphoma
chidamide + SHR2554
Sensitive: D – Preclinical