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BIOMARKER:

ETV6-NTRK3 fusion

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Other names: NTRK3, TRKC, Neurotrophic tyrosine kinase, receptor, type 3, ETV6, ETS Variant Transcription Factor 6, ETS Variant 6, Ets Variant Gene 6 (TEL Oncogene), ETS Translocation Variant 6, Transcription Factor ETV6, ETS-Related Protein Tel1, TEL, TEL1 Oncogene, TEL Oncogene, TEL/ABL, THC5, TEL1, Tel
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Entrez ID:
ETV6-NTRK3 fusion
Salivary Gland Cancer
larotrectinib
Sensitive
:
C3
ESMO 2022 - 3 weeks - (New C3)
ETV6-NTRK3 fusion
Acute Lymphocytic Leukemia
crizotinib
Sensitive
:
C3
ETV6-NTRK3 fusion
Head and Neck Cancer
crizotinib
Sensitive
:
C3
ETV6-NTRK3 fusion
Solid Tumor
entrectinib
Sensitive
:
C3
ETV6-NTRK3 fusion
Acute Myelogenous Leukemia
entrectinib
Sensitive
:
C3
ETV6-NTRK3 fusion
Fibrosarcoma
VAC
Resistant
:
C4
ETV6-NTRK3 fusion
Fibrosarcoma
larotrectinib
Sensitive
:
C4
ETV6-NTRK3 fusion
Fibrosarcoma
vincristine + dactinomycin
Resistant
:
C4
ETV6-NTRK3 fusion
Salivary Gland Cancer
entrectinib
Resistant
:
C4
ETV6-NTRK3 fusion
Breast Cancer
larotrectinib
Sensitive
:
C4
ETV6-NTRK3 fusion
Neuroendocrine Tumor
entrectinib
Sensitive
:
C4
ETV6-NTRK3 fusion
Glioma
larotrectinib
Sensitive
:
C4
ETV6-NTRK3 fusion
Soft Tissue Sarcoma
larotrectinib
Sensitive
:
C4
ETV6-NTRK3 fusion
Neuroblastoma
TPX-0005
Sensitive
:
D
ETV6-NTRK3 fusion
Acute Lymphocytic Leukemia
larotrectinib
Sensitive
:
D
ETV6-NTRK3 fusion
Acute Lymphocytic Leukemia
PLX7486
Sensitive
:
D
ETV6-NTRK3 fusion
Squamous Cell Carcinoma of Head and Neck
LY2801653
Sensitive
:
D