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BIOMARKER:
ER mutation
i
Other names:
ESR1, Era, ESR, NR3A1, ER, ER beta
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News alerts, weekly reports and conference planners
Entrez ID:
2099
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
ER Y537S (17)
ER D538G (11)
ESR1 mutation (9)
ER positive + ESR1 mutation (6)
ER Y537N (5)
ER negative + PIK3CA H1047R (2)
PIK3CA mutation + ESR1 mutation (2)
ER D538G + ER F404L (1)
ER E380Q (1)
ER E380Q + ER F404L (1)
ER F404L (1)
ER L536Q (1)
ER T594T (1)
ER Y537C (1)
ER rs2234693 (1)
ESR1 rs1801132 (1)
ESR1 rs2228480 (1)
ESR1 rs2234693T>C (1)
ESR1 rs9322354 (1)
HR positive + PIK3CA H1047R (1)
HR positive + PIK3CA H1047R + ER D538G (1)
HR positive + PIK3CA H1047R + PIK3CA D350G + ER D538G (1)
PIK3CA H1047R + PIK3CA D959N + ER E380Q (1)
PIK3CA mutation + ER mutation (1)
HER-2 negative + HR positive + ESR1 mutation + PIK3CA mutation (0)
ER Y537S (17)
ER D538G (11)
ESR1 mutation (9)
ER positive + ESR1 mutation (6)
ER Y537N (5)
ER negative + PIK3CA H1047R (2)
PIK3CA mutation + ESR1 mutation (2)
ER D538G + ER F404L (1)
ER E380Q (1)
ER E380Q + ER F404L (1)
ER F404L (1)
ER L536Q (1)
ER T594T (1)
ER Y537C (1)
ER rs2234693 (1)
ESR1 rs1801132 (1)
ESR1 rs2228480 (1)
ESR1 rs2234693T>C (1)
ESR1 rs9322354 (1)
HR positive + PIK3CA H1047R (1)
HR positive + PIK3CA H1047R + ER D538G (1)
HR positive + PIK3CA H1047R + PIK3CA D350G + ER D538G (1)
PIK3CA H1047R + PIK3CA D959N + ER E380Q (1)
PIK3CA mutation + ER mutation (1)
HER-2 negative + HR positive + ESR1 mutation + PIK3CA mutation (0)
›
Related tests:
Guardant360® CDx (54)
Guardant360® CDx (54)
Associations
News
Trials
VERI cancer hierarchy
Reset Filters
ER mutation
Estrogen Receptor Positive Breast Cancer
ER mutation
Estrogen Receptor Positive Breast Cancer
palbociclib
Sensitive: B - Late Trials
palbociclib
Sensitive
:
B
palbociclib
Sensitive: B - Late Trials
palbociclib
Sensitive
:
B
ER mutation
Breast Cancer
ER mutation
Breast Cancer
palbociclib
Resistant: B - Late Trials
palbociclib
Resistant
:
B
palbociclib
Resistant: B - Late Trials
palbociclib
Resistant
:
B
ER mutation
Hormone Receptor Positive Breast Cancer
ER mutation
Hormone Receptor Positive Breast Cancer
exemestane
Resistant: B - Late Trials
exemestane
Resistant
:
B
exemestane
Resistant: B - Late Trials
exemestane
Resistant
:
B
ER mutation
Estrogen Receptor Positive Breast Cancer
ER mutation
Estrogen Receptor Positive Breast Cancer
fulvestrant
Sensitive: B - Late Trials
fulvestrant
Sensitive
:
B
fulvestrant
Sensitive: B - Late Trials
fulvestrant
Sensitive
:
B
ER mutation
Estrogen Receptor Positive Breast Cancer
ER mutation
Estrogen Receptor Positive Breast Cancer
exemestane
Resistant: B - Late Trials
exemestane
Resistant
:
B
exemestane
Resistant: B - Late Trials
exemestane
Resistant
:
B
ER mutation
Hormone Receptor Positive Breast Cancer
ER mutation
Hormone Receptor Positive Breast Cancer
fulvestrant
Sensitive: B - Late Trials
fulvestrant
Sensitive
:
B
fulvestrant
Sensitive: B - Late Trials
fulvestrant
Sensitive
:
B
ER mutation
HER2 Negative Breast Cancer
ER mutation
HER2 Negative Breast Cancer
Aromatase inhibitor + palbociclib
Resistant: B - Late Trials
Aromatase inhibitor + palbociclib
Resistant
:
B
Aromatase inhibitor + palbociclib
Resistant: B - Late Trials
Aromatase inhibitor + palbociclib
Resistant
:
B
ER mutation
Breast Cancer
ER mutation
Breast Cancer
fulvestrant
Sensitive: C2 – Inclusion Criteria
fulvestrant
Sensitive
:
C2
fulvestrant
Sensitive: C2 – Inclusion Criteria
fulvestrant
Sensitive
:
C2
ER mutation
Estrogen Receptor Positive Breast Cancer
ER mutation
Estrogen Receptor Positive Breast Cancer
elacestrant
Sensitive: C2 – Inclusion Criteria
elacestrant
Sensitive
:
C2
elacestrant
Sensitive: C2 – Inclusion Criteria
elacestrant
Sensitive
:
C2
ER mutation
HER2 Negative Breast Cancer
ER mutation
HER2 Negative Breast Cancer
GDC-9545
Sensitive: C2 – Inclusion Criteria
GDC-9545
Sensitive
:
C2
GDC-9545
Sensitive: C2 – Inclusion Criteria
GDC-9545
Sensitive
:
C2
ER mutation
HER2 Negative Breast Cancer
ER mutation
HER2 Negative Breast Cancer
palbociclib + PF-05212384
Sensitive: C3 – Early Trials
palbociclib + PF-05212384
Sensitive
:
C3
palbociclib + PF-05212384
Sensitive: C3 – Early Trials
palbociclib + PF-05212384
Sensitive
:
C3
ER mutation
Breast Cancer
ER mutation
Breast Cancer
venetoclax
Sensitive: C3 – Early Trials
venetoclax
Sensitive
:
C3
venetoclax
Sensitive: C3 – Early Trials
venetoclax
Sensitive
:
C3
ER mutation
Estrogen Receptor Positive Breast Cancer
ER mutation
Estrogen Receptor Positive Breast Cancer
enobosarm
Sensitive: C3 – Early Trials
enobosarm
Sensitive
:
C3
enobosarm
Sensitive: C3 – Early Trials
enobosarm
Sensitive
:
C3
ER mutation
HER2 Negative Breast Cancer
ER mutation
HER2 Negative Breast Cancer
SAR439859
Sensitive: C3 – Early Trials
SAR439859
Sensitive
:
C3
SAR439859
Sensitive: C3 – Early Trials
SAR439859
Sensitive
:
C3
ER mutation
HER2 Negative Breast Cancer
ER mutation
HER2 Negative Breast Cancer
CDK4 inhibitor + CDK6 inhibitor
Resistant: C3 – Early Trials
CDK4 inhibitor + CDK6 inhibitor
Resistant
:
C3
CDK4 inhibitor + CDK6 inhibitor
Resistant: C3 – Early Trials
CDK4 inhibitor + CDK6 inhibitor
Resistant
:
C3
ER mutation
Hormone Receptor Positive Breast Cancer
ER mutation
Hormone Receptor Positive Breast Cancer
alpelisib
Resistant: C3 – Early Trials
alpelisib
Resistant
:
C3
alpelisib
Resistant: C3 – Early Trials
alpelisib
Resistant
:
C3
ER mutation
Estrogen Receptor Positive Breast Cancer
ER mutation
Estrogen Receptor Positive Breast Cancer
bevacizumab
Sensitive: C3 – Early Trials
bevacizumab
Sensitive
:
C3
bevacizumab
Sensitive: C3 – Early Trials
bevacizumab
Sensitive
:
C3
ER mutation
HER2 Negative Breast Cancer
ER mutation
HER2 Negative Breast Cancer
G1T48
Sensitive: C4 – Case Studies
G1T48
Sensitive
:
C4
G1T48
Sensitive: C4 – Case Studies
G1T48
Sensitive
:
C4
^
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