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BIOMARKER:

EML4-ALK variant 3

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Other names: EML4, EMAP Like 4, Restrictedly Overexpressed Proliferation-Associated Protein, Echinoderm Microtubule-Associated Protein-Like 4, Echinoderm Microtubule Associated Protein Like 4, Ropp 120, C2orf2, EMAP-4, EMAPL4, ROPP120, ELP120, NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor
Entrez ID:
EML4-ALK variant 3
Non Small Cell Lung Cancer
lorlatinib
Sensitive
:
B
EML4-ALK variant 3
Non Small Cell Lung Cancer
crizotinib
Resistant
:
C3
EML4-ALK variant 3
Non Small Cell Lung Cancer
ceritinib
Sensitive
:
C3
EML4-ALK variant 3
Lung Adenocarcinoma
Angiogenesis inhibitor
Resistant
:
C4
EML4-ALK variant 3
Lung Adenocarcinoma
Immunotherapy
Resistant
:
C4
EML4-ALK variant 3
Non Small Cell Lung Cancer
alectinib
Sensitive
:
C4
EML4-ALK variant 3
Non Small Cell Lung Cancer
paclitaxel
Sensitive
:
D
EML4-ALK variant 3
Non Small Cell Lung Cancer
brigatinib
Sensitive
:
D