^
    BIOMARKER:

    EML4-ALK variant 3 + TP53 mutation

    i
    Other names: NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor, EML4, EMAP Like 4, Restrictedly Overexpressed Proliferation-Associated Protein, Echinoderm Microtubule-Associated Protein-Like 4, Echinoderm Microtubule Associated Protein Like 4, Ropp 120, C2orf2, EMAP-4, EMAPL4, ROPP120, ELP120, TP53, Tumor Protein P53, Cellular Tumor Antigen P53, Phosphoprotein P53, Tumor Protein P53, Antigen NY-CO-13, Transformation-Related Protein 53, Mutant Tumor Protein 53, P53 Tumor Suppressor, Tumor Suppressor P53, Tumor Protein 53, BMFS5, TRP53, BCC7, LFS1
    Entrez ID:
    238; 7157; 27436
    Related biomarkers:
    Expression
    Mutation
    CNA
    Fusion
    Others

    Associations

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    Trials
    EML4-ALK variant 3 + TP53 mutation
    LUAD
    alectinib
    Resistant: C4 – Case Studies
    EML4-ALK variant 3 + TP53 mutation
    LUAD
    brigatinib
    Resistant: C4 – Case Studies
    EML4-ALK variant 3 + TP53 mutation
    LUAD
    lorlatinib
    Resistant: D – Preclinical
    EML4-ALK variant 3 + TP53 mutation
    LUAD
    crizotinib
    Sensitive: D – Preclinical