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BIOMARKER:
EGFR mutation + PIK3CA mutation
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor, PIK3CA, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha, Phosphoinositide-3-kinase, catalytic, alpha polypeptide, Serine/threonine protein kinase PIK3CA, PtdIns-3-kinase subunit P110-alpha, PI3K-alpha, Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 KDa catalytic subunit alpha, Phosphatidylinositol 3-kinase, Catalytic, 110-KD, alpha, PI3-kinase P110 subunit alpha, PI3-kinase subunit alpha, PtdIns-3-kinase subunit alph
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Entrez ID:
1956
;
5290
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR-RAD51 fusion (5)
EGFR-SEPTIN14 fusion (2)
EGFR fusion (1)
EGFR-GRB2 fusion (1)
KIF5B-EGFR fusion (1)
EGFR fusion + RAD51 fusion (0)
EGFR-RAD51 fusion (5)
EGFR-SEPTIN14 fusion (2)
EGFR fusion (1)
EGFR-GRB2 fusion (1)
KIF5B-EGFR fusion (1)
EGFR fusion + RAD51 fusion (0)
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VERI cancer hierarchy
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EGFR mutation + PIK3CA mutation
Lung Adenocarcinoma
EGFR mutation + PIK3CA mutation
Lung Adenocarcinoma
Tyrosine kinase inhibitor
Resistant: C3 – Early Trials
Tyrosine kinase inhibitor
Resistant
:
C3
Tyrosine kinase inhibitor
Resistant: C3 – Early Trials
Tyrosine kinase inhibitor
Resistant
:
C3
EGFR mutation + PIK3CA mutation
Non Small Cell Lung Cancer
EGFR mutation + PIK3CA mutation
Non Small Cell Lung Cancer
Tyrosine kinase inhibitor
Resistant: C3 – Early Trials
Tyrosine kinase inhibitor
Resistant
:
C3
Tyrosine kinase inhibitor
Resistant: C3 – Early Trials
Tyrosine kinase inhibitor
Resistant
:
C3
EGFR mutation + PIK3CA mutation
Non Small Cell Lung Cancer
EGFR mutation + PIK3CA mutation
Non Small Cell Lung Cancer
aumolertinib
Sensitive: C3 – Early Trials
aumolertinib
Sensitive
:
C3
aumolertinib
Sensitive: C3 – Early Trials
aumolertinib
Sensitive
:
C3
EGFR mutation + PIK3CA mutation
Lung Adenocarcinoma
EGFR mutation + PIK3CA mutation
Lung Adenocarcinoma
aumolertinib
Sensitive: C4 – Case Studies
aumolertinib
Sensitive
:
C4
aumolertinib
Sensitive: C4 – Case Studies
aumolertinib
Sensitive
:
C4
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