Advanced NSCLC patients harboring EGFR sensitive mutations (19DEL/L858R) after resistant to EGFR-TKIs and received anti-PD1/PD-L1 based treatment any lines were retrospectively analyzed...EGFR mutated NSCLC patients with short PFS to EGFR-TKIs conferred better response to following anti-PD-1/PD-L1 based immunotherapy.