MYCN amplification	Neuroblastoma	MYCN amplification	Neuroblastoma	DHODH inhibitor Sensitive: D – Preclinical DHODH inhibitor Sensitive : D	DHODH inhibitor Sensitive: D – Preclinical DHODH inhibitor Sensitive : D
MYC rearrangement + BCL2 rearrangement	Lymphoma	MYC rearrangement + BCL2 rearrangement	Lymphoma	venetoclax + DUP 785 Sensitive: D – Preclinical venetoclax + DUP 785 Sensitive : D	venetoclax + DUP 785 Sensitive: D – Preclinical venetoclax + DUP 785 Sensitive : D
TP53 mutation	Acute Myelogenous Leukemia	TP53 mutation	Acute Myelogenous Leukemia	DHODH inhibitor Sensitive: D – Preclinical DHODH inhibitor Sensitive : D	DHODH inhibitor Sensitive: D – Preclinical DHODH inhibitor Sensitive : D
FLT3-ITD mutation	Acute Myelogenous Leukemia	FLT3-ITD mutation	Acute Myelogenous Leukemia	gilteritinib + DUP 785 Sensitive: D – Preclinical gilteritinib + DUP 785 Sensitive : D	gilteritinib + DUP 785 Sensitive: D – Preclinical gilteritinib + DUP 785 Sensitive : D
TP53 deletion	Acute Lymphocytic Leukemia	TP53 deletion	Acute Lymphocytic Leukemia	M6620 + BAY2402234 Sensitive: D – Preclinical M6620 + BAY2402234 Sensitive : D	M6620 + BAY2402234 Sensitive: D – Preclinical M6620 + BAY2402234 Sensitive : D

DHODH inhibitor

Associations(5)