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Association details:
Biomarker:DDB1 overexpression
Cancer:Multiple Myeloma
Drug:thalidomide (TNF inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
Title:

EXPRESSION SIGNIFICANCE OF CRL4-CRBN PROTEINS COMPLEX IN MULTIPLE MYELOMA PATIENTS TREATED WITH IMMUNOMODULATORY DRUGS.

Published date:
05/14/2020
Excerpt:
The high DDB1 expression, as the only one, was associated with longer OS of MM patients treated with thalidomide or lenalidomide (p=0.002).