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GENE:
CTLA4 (Cytotoxic T-Lymphocyte Associated Protein 4)
i
Other names:
CTLA4, Cytotoxic T-Lymphocyte Associated Protein 4, Insulin-Dependent Diabetes Mellitus 12, Cytotoxic T-Lymphocyte Protein 4, Celiac Disease 3, CTLA-4, CD152, Ligand And Transmembrane Spliced Cytotoxic T Lymphocyte Associated Antigen 4, Cytotoxic T Lymphocyte Associated Antigen 4 Short Spliced Form, Cytotoxic T-Lymphocyte-Associated Serine Esterase-4, Cytotoxic T-Lymphocyte-Associated Antigen 4, CD152 Isoform, CD152 Antigen, CELIAC3, IDDM12, ALPS5, GRD4
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Entrez ID:
1493
Related tests:
‹
HTG EdgeSeq Oncology Biomarker Panel (OBP) (2)
Archer® FusionPlex® Lymphoma
FusionPlex™ Pan-Heme panel
HTG EdgeSeq DLBCL Cell of Origin Assay
HTG EdgeSeq DLBCL Cell of Origin Assay EU
Solid Tumor Profile Plus
TheraMap Test
HTG EdgeSeq Oncology Biomarker Panel (OBP) (2)
Archer® FusionPlex® Lymphoma
FusionPlex™ Pan-Heme panel
HTG EdgeSeq DLBCL Cell of Origin Assay
HTG EdgeSeq DLBCL Cell of Origin Assay EU
Solid Tumor Profile Plus
TheraMap Test
›
Associations
(14)
News
Trials
VERI cancer hierarchy
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CTLA4 overexpression
Soft Tissue Sarcoma
CTLA4 overexpression
Soft Tissue Sarcoma
trabectedin
Sensitive: C3 – Early Trials
trabectedin
Sensitive
:
C3
trabectedin
Sensitive: C3 – Early Trials
trabectedin
Sensitive
:
C3
CTLA4 overexpression
Mantle Cell Lymphoma
CTLA4 overexpression
Mantle Cell Lymphoma
ibrutinib + rituximab
Sensitive: C3 – Early Trials
ibrutinib + rituximab
Sensitive
:
C3
ibrutinib + rituximab
Sensitive: C3 – Early Trials
ibrutinib + rituximab
Sensitive
:
C3
CTLA4 expression
Non Small Cell Lung Cancer
CTLA4 expression
Non Small Cell Lung Cancer
atezolizumab
Sensitive: C3 – Early Trials
atezolizumab
Sensitive
:
C3
atezolizumab
Sensitive: C3 – Early Trials
atezolizumab
Sensitive
:
C3
CTLA4 promoter hypomethylation
Clear Cell Renal Cell Carcinoma
CTLA4 promoter hypomethylation
Clear Cell Renal Cell Carcinoma
PD1 inhibitor
Sensitive: C3 – Early Trials
PD1 inhibitor
Sensitive
:
C3
PD1 inhibitor
Sensitive: C3 – Early Trials
PD1 inhibitor
Sensitive
:
C3
CTLA4 overexpression
Triple Negative Breast Cancer
CTLA4 overexpression
Triple Negative Breast Cancer
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
CTLA4 underexpression
Urothelial Cancer
CTLA4 underexpression
Urothelial Cancer
nivolumab + cabozantinib tablet
Sensitive: C3 – Early Trials
nivolumab + cabozantinib tablet
Sensitive
:
C3
nivolumab + cabozantinib tablet
Sensitive: C3 – Early Trials
nivolumab + cabozantinib tablet
Sensitive
:
C3
CTLA4 expression
Cutaneous Melanoma
CTLA4 expression
Cutaneous Melanoma
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
ITGAM overexpression + CTLA4 overexpression
Gastric Cancer
ITGAM overexpression + CTLA4 overexpression
Gastric Cancer
nivolumab
Sensitive: C3 – Early Trials
nivolumab
Sensitive
:
C3
nivolumab
Sensitive: C3 – Early Trials
nivolumab
Sensitive
:
C3
ALK rearrangement + CTLA4 overexpression
Non Small Cell Lung Cancer
ALK rearrangement + CTLA4 overexpression
Non Small Cell Lung Cancer
ALK inhibitor
Resistant: C3 – Early Trials
ALK inhibitor
Resistant
:
C3
ALK inhibitor
Resistant: C3 – Early Trials
ALK inhibitor
Resistant
:
C3
CTLA4 overexpression
Triple Negative Breast Cancer
CTLA4 overexpression
Triple Negative Breast Cancer
carboplatin + docetaxel
Sensitive: C3 – Early Trials
carboplatin + docetaxel
Sensitive
:
C3
carboplatin + docetaxel
Sensitive: C3 – Early Trials
carboplatin + docetaxel
Sensitive
:
C3
CTLA4 promoter hypomethylation
Squamous Cell Carcinoma of Head and Neck
CTLA4 promoter hypomethylation
Squamous Cell Carcinoma of Head and Neck
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
CTLA4 overexpression
Melanoma
CTLA4 overexpression
Melanoma
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
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