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    Association details:
    Biomarker:Chr del(1p)
    Cancer:Glioma
    Drug:vincristine (Tubulin polymerization inhibitor) +
    lomustine (Alkylating agent) +
    Matulane (procarbazine hydrochloride) (Alkylating agent)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: C3 – Early Trials
    New
    Source:
    J Natl Cancer Inst
    Title:

    Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas

    Excerpt:
    The loss of chromosome 1p was a statistically significant predictor of survival…
    DOI:
    10.1093/jnci/90.19.1473