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BIOMARKER:
CDKN2A Negative + NRAS Mutation
i
Other names:
NRAS1, N-Ras Protein Part 4, Neuroblastoma RAS Viral (V-Ras) Oncogene Homolog, NRAS, Neuroblastoma RAS Viral Oncogene Homolog, NRAS Proto-Oncogene, GTPase, CDKN2A, ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf, Cyclin-dependent kinase inhibitor 2A
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Entrez ID:
4893
;
1029
Related biomarkers:
Expression
Mutation
CNA
Others
‹
EGFR exon 19 deletion + NRAS Q61K (3)
PD-L1 expression + NRAS Q61R + BRAF D594N (2)
CDKN2A promoter methylation (2)
Chr t(11;14) + NRAS mutation (1)
KRAS wild-type + NRAS wild-type + MSI-H/dMMR (1)
MLL-AFF1 fusion + NRAS mutation (1)
NRAS mutation + BRAF wild-type (1)
NRAS wild-type + NOTCH4 mutation (1)
ALK rearrangement + CDKN2A deletion (1)
BAP1 mutation + IDH2 R172W + CDKN2A deletion + CDKN2B deletion (1)
BRAF V600E + CDKN2A deletion + MYCN amplification (1)
BRAF V600E + CDKN2A deletion + RB1 expression (1)
BRAF V600K + CDKN2A deletion + RB1 expression (1)
CDKN2A deletion + CDKN2B deletion + MTAP deletion + TERT mutation (1)
CDKN2A mutation + PD-L1 overexpression (1)
CDKN2A mutation + TMB-H (1)
EGFR mutation + CCND1 expression + CDKN2A deletion (1)
NF1 mutation + CDKN2A deletion + CDKN2B deletion + MTAP deletion (1)
TMB-L + ARID1A deletion + CDKN2A deletion + CDKN2B deletion + MTAP deletion + PIK3R1 N564D + NBN P81fs*23 (1)
EGFR exon 19 deletion + NRAS Q61K (3)
PD-L1 expression + NRAS Q61R + BRAF D594N (2)
CDKN2A promoter methylation (2)
Chr t(11;14) + NRAS mutation (1)
KRAS wild-type + NRAS wild-type + MSI-H/dMMR (1)
MLL-AFF1 fusion + NRAS mutation (1)
NRAS mutation + BRAF wild-type (1)
NRAS wild-type + NOTCH4 mutation (1)
ALK rearrangement + CDKN2A deletion (1)
BAP1 mutation + IDH2 R172W + CDKN2A deletion + CDKN2B deletion (1)
BRAF V600E + CDKN2A deletion + MYCN amplification (1)
BRAF V600E + CDKN2A deletion + RB1 expression (1)
BRAF V600K + CDKN2A deletion + RB1 expression (1)
CDKN2A deletion + CDKN2B deletion + MTAP deletion + TERT mutation (1)
CDKN2A mutation + PD-L1 overexpression (1)
CDKN2A mutation + TMB-H (1)
EGFR mutation + CCND1 expression + CDKN2A deletion (1)
NF1 mutation + CDKN2A deletion + CDKN2B deletion + MTAP deletion (1)
TMB-L + ARID1A deletion + CDKN2A deletion + CDKN2B deletion + MTAP deletion + PIK3R1 N564D + NBN P81fs*23 (1)
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CDKN2A Negative + NRAS Mutation
Melanoma
CDKN2A Negative + NRAS Mutation
Melanoma
abemaciclib
Sensitive: C4 – Case Studies
abemaciclib
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:
C4
abemaciclib
Sensitive: C4 – Case Studies
abemaciclib
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